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Immunocytochemical study of Ki-67 as a prognostic marker in canine mammary neoplasia
(2004-03-01)
Background: Canine mammary tumors are challenging for clinicians and pathologists because of complex histologic classification, low specificity of cytologic diagnosis, and unpredictable biological behavior. In histologic ...
STEAP1 protein overexpression is an independent marker for biochemical recurrence in prostate carcinoma
(2013-09-16)
Aims: To investigate the prognostic value of expression levels of the genes STEAP1 and STEAP2, and of STEAP1 protein, in prostate carcinomas (PCa). Methods and results: STEAP1 and STEAP2 transcript levels were evaluated ...
TGF beta R2 aberrant methylation is a potential prognostic marker and therapeutic target in multiple myeloma
(Wiley-Blackwell, 2009-10-15)
Multiple myeloma (MM) is an incurable hematological malignancy. Different studies demonstrated the occurrence of genetic and epigenetic alterations in MM. the aberrant methylation is one of the most frequent epigenetic ...
Quality of life as a prognostic marker in pulmonary arterial hypertension
(Biomed Central Ltd, 2014-08-30)
Background: Improvement in quality of life together with better survival are the ultimate goals in the treatment of pulmonary arterial hypertension (PAH) patients. the objective of this study was to evaluate the health-related ...
SFlt-1/PlGF ratio as a prognostic marker of adverse outcomes in women with early-onset preeclampsia
(2013-07-01)
Soluble fms-like tyrosine kinase 1 (sFlt-1) is an anti-angiogenic factor released in higher amounts by preeclamptic placentas and it has been implicated in the endothelial dysfunction observed in the disease. In this study ...
Homeostase do cálcio e marcadores do metabolismo ósseo no hipertireoidismo felino - Revisão
(2007-11-22)
Hyperthyroidism is the most frequent endocrine disease in old-aged cats. It is a illness provoked by the excess of circulating thyroid hormones. Hyperthyroidism causes alteration in bone metabolism with predominance of ...
Ki-67 and CD100 immunohistochemical expression is associated with local recurrence and poor prognosis in soft tissue sarcomas, respectively
(2013-10-01)
Soft tissue sarcomas (STSs) are a heterogeneous group of mesenchymal tumors of >50 subtypes. However, STSs represent <1% of types of cancer. Despite this low frequency, the disease is aggressive and treatment, when possible, ...
Pró-calcitonina e proteína C reativa em processos infecciosos graves
(Sociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de Citopatologia, 2004-06-01)
Biochemical markers for septic processes are necessary in order to obtain objective evidence of sepsis. The C-reactive protein (CRP) has been used to that, despite its low specificity. The procalcitonin (PCT) was proposed ...
Prognostic markers of low-grade squamous intraepithelial lesions: the role of topoisomerase II alpha and active caspase-3
(I R O G Canada, Inc, 2008-01-01)
Purpose: To study the relationship between topoisomerase II alpha, active caspase-3 expressions and HPV DNA in uterine cervices with low-grade squamous intraepithelial lesions (LSIL). Methods: Forty women with LSIL and 32 ...