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Alterations of the CCND1 and HER-2/neu (ERBB2) proteins in esophageal and gastric cancers
(Elsevier B.V., 2006-02-01)
We evaluated the relationship of amplification and polysomy of both the CCND1 and the ERBB2 (alias HER-2/NEU) genes to the overexpression of their proteins in esophageal and gastric cancers and also their association with ...
Polymorphisms of DNA repair genes XRCC1 and XRCC3, interaction with environmental exposure and risk of chronic gastritis and gastric cancer
(Baishideng Publ Grp Co Ltd, 2005-11-14)
AIM: To evaluate the association between polymorphisms XRCC1 Arg194Trp and Arg399Gln and XRCC3 Thr241Met and the risk for chronic gastritis and gastric cancer, in a Southeastern Brazilian population.METHODS: Genotyping by ...
Infecção por Helicobacter pylori e câncer gástrico: freqüência de cepas patogênicas cagA e vacA em pacientes com câncer gástrico
(Sociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de Citopatologia, 2006-02-01)
INTRODUÇÃO: Apesar da alta freqüência de infecção por Helicobacter pylori na população, somente uma minoria de indivíduos desenvolve câncer gástrico. É provável que a colonização da mucosa por cepas patogênicas, levando a ...
Relationship among oxidative DNA damage, gastric mucosal density and the relevance of cagA, vacA and iceA genotypes of Helicobacter pylori
(Springer, 2008-01-01)
The aim of this study was to evaluate the relationship among oxidative DNA damage, density of Helicobacter pylori and the relevance of cagA, vacA and iceA genotypes of H. pylori. Gastric epithelial cells were isolated from ...
Digit ratio (2D:4D) is associated with gastric cancer
(2013-05-01)
Background: Sex steroid exposure during early human development may influence disease susceptibility. Digit ratio (2D:4D) is a putative marker for prenatal hormone exposure and sensitivity, as well as the action of genes ...
IL-1ra anti-inflammatory cytokine polymorphism is associated with risk of gastric cancer and chronic gastritis in a Brazilian population, but the TNF-beta pro-inflammatory cytokine is not
(Springer, 2012-07-01)
Genetic polymorphisms in genes that codify inflammatory cytokines have been associated with gastric carcinogenesis. This study evaluated polymorphisms IL-1RN VNTR and TNFB+252A/G in a population from Southeast Brazil with ...
Differential expression of histone deacetylase and acetyltransferase genes in gastric cancer and their modulation by trichostatin A
(Springer, 2014-07-01)
Gastric cancer is still the second leading cause of cancer-related death worldwide, even though its incidence and mortality have declined over the recent few decades. Epigenetic control using histone deacetylase inhibitors, ...
Genomic alterations in diffuse-type gastric cancer as shown by high-resolution comparative genomic hybridization
(Elsevier B.V., 2009-04-01)
Gastric adenocarcinoma is a serious public health concern, especially in northern Brazil. Gastric cancer call be subdivided into diffuse and intestinal types. Genetic imbalances in diffuse-type gastric cancer remain largely ...
Gastric cancer is associated with NOS2-954G/C polymorphism and environmental factors in a Brazilian population
(Biomed Central Ltd., 2015)