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Gastric adenocarcinoma and Helicobacter pylori: Correlation with p53 mutation and p27 immunoexpression
(Elsevier B.V., 2010-10-01)
Introduction: Helicobacter pylori infection is an established risk factor for gastric cancer development, but the exact underlying mechanism still remains obscure. The inactivation of tumor suppressor genes such as p53 and ...
Inactivation of COX-2, HMLH1 and CDKN2A Gene by Promoter Methylation in Gastric Cancer: Relationship with Histological Subtype, Tumor Location and Helicobacter pylori Genotype
(Karger, 2011-01-01)
Objective: We aimed to evaluate the inactivation of COX-2, HMLH1 and CDKN2A by promoter methylation and its relationship with the infection by different Helicobacter pylori strains in gastric cancer. Methods: DNA extracted ...
Epstein-Barr Virus microRNAs in the pathogenesis of human cancers
(Elsevier, 2020-11)
The Epstein-Barr Virus (EBV) is a gamma-herpesvirus involved with a variety of human cancers, notably the endemic Burkitt lymphoma and nasopharyngeal carcinoma. In 2004, EBV was described as one the first known human ...
Asociación del polimorfismo del codon 72 del gen P53 con el riesgo de cáncer gástrico en una población de alto riesgo de Costa Rica
(Revista de Biología Tropical 53 (3-4): 317-324, 2005, 2005-10-03)
El cáncer gástrico es la segunda causa de muerte por cáncer en el mundo. Varios factores han sido asociados con el riesgo de llegar a desarrollarlo, entre ellos la predisposición genética. El gen p53 presenta un polimorfismo ...
Helicobacter pylori: La revolución bacteriológica
(Sociedad Médica de Santiago, 1999)
Deregulation of Annexin-A1 and Galectin-1 Expression in Precancerous Gastric Lesions: Intestinal Metaplasia and Gastric Ulcer
(Hindawi Publishing Corporation, 2014-01-01)
Objective. Annexin-A1 (ANXA1/AnxA1) and galectin-1 (LGALS1/Gal-1) are mediators that play an important role in the inflammatory response and are also associated with carcinogenesis. We investigated mRNA and protein expression ...
Differential Proteomic Analysis of Noncardia Gastric Cancer from Individuals of Northern Brazil
(PUBLIC LIBRARY SCIENCESAN FRANCISCO, 2012)
Gastric cancer is the second leading cause of cancer-related death worldwide. The identification of new cancer biomarkers is necessary to reduce the mortality rates through the development of new screening assays and early ...
Association Of Common Variants On Chromosome 8q24 With Gastric Cancer In Venezuelan Patients
(ELSEVIER SCIENCE BVAMSTERDAM, 2015)
Pepsinógenos séricos para detectar cáncer gástrico en Costa Rica
(Ada Bioquirnice Minion Latinoamericana ; 37 (4): 357-62, 2003)
Las concentraciones de pepsinagenos (PG) I y II en suero, reflejan el estado funcional y morfológico de la mucosa gástrica. En este estudio se determinaron los puntos de corte óptimos de los niveles séricos de PGI, PGII y ...
Peripheral position of CCND1 and HER-2/neu oncogenes within chromosome territories in esophageal and gastric cancers non-related to amplification and overexpression
(Sociedade Brasileira de Genética, 2009-01-01)
Interphase chromosomes have been shown to occupy discrete regions of the nucleus denominated chromosome territories (CTs), their active genes being preferentially positioned on the surfaces of these CTs, where they are ...