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Propolis: lymphocyte proliferation and IFN-gamma production
(Elsevier B.V., 2003-07-01)
We evaluated propolis influence on polyclonal activation of lymphocytes by concanavalin A (Con A). The in vitro experiments showed that propolis decreases splenocyte proliferation both in the absence or presence of Con A. ...
Propolis and the immune system: a review
(Elsevier B.V., 2007-08-15)
Propolis has been used empirically for centuries and it was always mentioned as an immunomodulatory agent. In recent years, in vitro and in vivo assays provided new information concerning its mechanisms of action, thus a ...
Byrsonima fagifolia: An integrative study to validate the gastroprotective, healing, antidiarrheal, antimicrobial and mutagenic action
(Elsevier B.V., 2008-11-20)
Ethnopharmacological relevance: Ethnopharmacological survey indicated leaves of Byrsonima fagifolia Nied. (Malpighiaceae) against gastrointestinal disorders.Aim of the study:The methanolic extract from the leaves of Byrsonima ...
A new chemotherapeutic approach using doxorubicin simultaneously with geopropolis favoring monocyte functions
(2019-01-15)
Aims: Chemotherapy has been widely used to treat cancer although it may affect non-target cells involved in the immune response. This work aimed at elucidating whether the chemotherapeutic agent doxorubicin in combination ...
Crotoxin: Novel activities for a classic beta-neurotoxin
(Pergamon-Elsevier B.V. Ltd, 2010-06-01)
Crotoxin, the main toxin of South American rattlesnake (Crotalus durissus terrificus) venom, was the first snake venom protein to be purified and crystallized. Crotoxin is a heterodimeric beta-neurotoxin that consists of ...
Tityus serrulatus venom and toxins Ts1, Ts2 and Ts6 induce macrophage activation and production of immune mediators
(PERGAMON-ELSEVIER SCIENCE LTD, 2011)
Scorpion envenomation induces a systemic immune response, and neurotoxins of venom act on specific ion channels, modulating neurotransmitter release or activity. However, little is known about the immunomodulatory effects ...
Propolis and its constituent caffeic acid suppress LPS-stimulated pro-inflammatory response by blocking NF-κB and MAPK activation in macrophages
(2013-08-26)
Ethnopharmacological relevance Propolis is a bee product with numerous biological and pharmacological properties, such as immunomodulatory and anti-inflammatory activities. It has been used in folk medicine as a healthy ...
Lack of Chemopreventive Activity of Agaricus blazei Mushroom on the Development of 1,2-Dimethylhydrazine-Induced Colonic Aberrant Crypt Foci in Rats
(Lawrence Erlbaum Assoc Inc-taylor & Francis, 2008-01-01)
Chemopreventive and immunomodulatory potential of methanolic (MET) and dichloromethanic (DCl) extracts of Agaricus blazei mushroom were investigated in the postinitiation stage of colon carcinogenesis in male Wistar rats. ...
Propolis modulates miRNAs involved in TLR-4 pathway, NF-κB activation, cytokine production and in the bactericidal activity of human dendritic cells
(2016-12-01)
Objectives: Dendritic cells (DCs) are antigen-presenting cells, essential for recognition and presentation of pathogens to T cells. Propolis, a resinous material produced by bees from various plants, exhibits numerous ...
The Effects of Propolis and its Isolated Compounds on Cytokine Production by Murine Macrophages
(Wiley-Blackwell, 2012-09-01)
Since propolis and phenolic compounds, such as cinnamic and coumaric acids, have several biological properties, their immunomodulatory effect on cytokine production (IL-1 beta, IL-6 and IL-10) was investigated. Peritoneal ...