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Leishmania encodes a bacterium-like 2,4-dienoyl-coenzyme a reductase that is required for fatty acid β-oxidation and intracellular parasite survival
(2020-05-01)
Leishmania spp. are protozoan parasites that cause a spectrum of important diseases in humans. These parasites develop as extracellular promastigotes in the digestive tract of their insect vectors and as obligate intracellular ...
Macrophage migration inhibitory factor in the nucleus of solitary tract decreases blood pressure in SHRs
(2013-01-01)
Aims The macrophage migration inhibitory factor (MIF) is an intracellular inhibitor of the central nervous system actions of angiotensin II on blood pressure. Considering that angiotensin II actions at the nucleus of the ...
Aberrant expression of E-cadherin and beta-catenin proteins in placenta of bovine embryos derived from somatic cell nuclear transfer
(CSIRO Publishing, 2012-01-01)
Abnormal placental development is common in the bovine somatic cell nuclear transfer (SCNT)-derived fetus. In the present study, we characterised the expression of E-cadherin and beta-catenin, structural proteins of adherens ...
New transposons to generate GFP protein fusions in Candida albicans
(ELSEVIER SCIENCE BV, 2008)
Transposon elements are important tools for gene function analysis, for example they can be used to easily create genome-wide collections of insertion mutants. Transposons may also carry sequences coding for an epitope or ...
New insights into plant natriuretic peptide evolution: From the lysogenic conversion in Xanthomonas to the lateral transfer to the whitefly Bemisia tabaci
(2022-05-05)
Plant natriuretic peptide-like (PNP) are signaling molecules related to adaptive responses to stress. The Arabidopsis thaliana PNP (AtPNP-A) is capable of modulating catalase 2 (CAT2) and rubisco activase (RCA) activity ...
MTP -493G/T gene polymorphism is associated with steatosis in hepatitis C-infected patients
(Associação Brasileira de Divulgação Científica, 2012)
The reduction of hepatic microsomal transfer protein (MTP) activity results in fatty liver, worsening hepatic steatosis and fibrosis in chronic hepatitis C (CHC). The G allele of the MTP gene promoter, -493G/T, has been ...