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15d-prostaglandin J(2) inhibits inflammatory hypernociception: Involvement of peripheral opioid receptor
(AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, 2008)
The 15-deoxy-Delta(12,14)-prostaglandin J(2) (15d-PGJ(2)) is an endogenous ligand of peroxisome proliferator-activated receptors gamma (PPAR-gamma) and is now recognized as a potent anti-inflammatory mediator. However, ...
Pro-apoptotic effect of anti-β1-adrenergic receptor antibodies in periodontitis patients
(Elsevier Science, 2012-12)
An anti-β1-adrenergic antibody from the sera of periodontitis patients (anti-β1-AR IgG) against the second extracellular loop of the human β1-adrenoceptor (β1-AR) has been shown to cause rat atria apoptosis. The anti-β1-AR ...
Long-term treatment with methanandamide attenuates LPS-induced periodontitis in rats
(Birkhauser Verlag Ag, 2012-09)
OBJECTIVE: Evidence exists of the anti-inflammatory and immunological properties of endocannabinoids in various tissues; the aim of the present study was therefore to assess the effect of long-term treatment with the ...
Exenatide and sitagliptin decrease interleukin 1β, matrix metalloproteinase 9, and nitric oxide synthase 2 gene expression but does not reduce alveolar bone loss in rats with periodontitis
(Journal of Periodontology, 2015)
New drugs for the treatment of diabetes, glucagon-like peptide-1 (GLP-1) receptor agonists and inhibitors of dipeptidyl peptidase-4 (DPP-4) have shown pleiotropic effects on bone metabolism and anti-inflammatory properties. ...
Peroxisome proliferator-activated receptor-gamma ligand, 15-deoxy-Delta A(12,14)-prostaglandin J(2), reduces neutrophil migration via a nitric oxide pathway
(AMER ASSOC IMMUNOLOGISTS, 2008)
Ligands for peroxisome proliferator-activated receptor gamma (PPAR-gamma), such as 15-deoxy-Delta(12,14)-prostaglandin J(2) (15d-PGJ(2)) have been implicated as a new class of anti-inflammatory compounds with possible ...
Antioxidative action of methanolic extract and buthanolic fraction of Vochysia tucanorum Mart. in the gastroprotection
(Elsevier Ireland LtdClareIrlanda, 2009)
Pharmacological characterization of mouse hind paw oedema induced by Bothrops insularis (jararaca ilhoa) snake venom
(Pergamon-elsevier Science LtdOxfordInglaterra, 2003)