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A complex interplay of genetic and epigenetic events leads to abnormal expression of the DUX4 gene in facioscapulohumeral muscular dystrophy
(Pergamon-Elsevier Science Ltd, 2016-12)
Facioscapulohumeral muscular dystrophy (FSHD), a prevalent inherited human myopathy, develops following a complex interplay of genetic and epigenetic events. FSHD1, the more frequent genetic form, is associated with: (1) ...
Dysferlin function in skeletal muscle: Possible pathological mechanisms and therapeutical targets in dysferlinopathies
(2016)
Mutations in the dysferlin gene are linked to a group of muscular dystrophies known as dysferlinopathies. These myopathies are characterized by progressive atrophy. Studies in muscle tissue from dysferlinopathy patients ...
Growth hormone attenuates skeletal muscle changes in experimental chronic heart failure
(Churchill Livingstone, 2010-04-01)
Objective: This study evaluated the effects of growth hormone (GH) on morphology and myogenic regulatory factors (MRF) gene expression in skeletal muscle of rats with ascending aortic stenosis (AAS) induced chronic heart ...
Aspectos clínicos e concentração sérica da creatina-quinase e lactato-desidrogenase em cães submetidos à fisioterapia após atrofia muscular induzida
(Universidade Federal de Santa Maria (UFSM), 2011-07-01)
Avaliou-se a resposta de diferentes protocolos fisioterapêuticos em cães após a indução de atrofia muscular por meio da imobilização do joelho por 30 dias. Os grupos foram denominados grupo C ou controle, grupo E (massagem, ...
Eletroestimulação seletiva mantem estrutura e função do tibial anterior desnervado de ratos
(Atha Comunicação & Editora, 2010)
OBJETIVO: A eletroestimulação para tratamento de músculos desnervados deve ser aplicada através do tratamento seletivo. Este estudo avaliou o efeito da eletroestimulação seletiva do músculo desnervado sobre sua estrutura ...
Electrical Stimulation During Gait Promotes Increase of Muscle Cross-sectional Area in Quadriplegics: A Preliminary Study
(SPRINGEREstados Unidos, 2009)
Evaluation of muscle strength and motor abilities in children with type II and III spinal muscle atrophy treated with valproic acid
(BIOMED CENTRAL LTD, 2011)
Background: Spinal muscular atrophy (SMA) is an autosomal recessive disorder that affects the motoneurons of the spinal anterior horn, resulting in hypotonia and muscle weakness. The disease is caused by deletion or mutation ...