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In vitro effect of triamcinolone and platelet-rich plasma on cytokine levels of elbow lateral epicondylitis-derived cells
(2022-12-01)
Background: The pathogenesis and treatment of lateral elbow epicondylitis (LEE) are still controversial. The purpose of the current study was to evaluate the production of inflammatory cytokines by LEE-derived cells and ...
Blocking IL-10 signaling with soluble IL-10 receptor restores in vitro specific lymphoproliferative response in dogs with leishmaniasis caused by Leishmania infantum
(2021-01-01)
rIL-10 plays a major role in restricting exaggerated inflammatory and immune responses, thus preventing tissue damage. However, the restriction of inflammatory and immune responses by IL-10 can also favor the development ...
IL-17 mediates articular hypernociception in antigen-induced arthritis in mice
(ELSEVIER SCIENCE BV, 2010)
IL-17 is an important cytokine in the physiopathology of rheumatoid arthritis (RA). However, its participation in the genesis of nociception during RA remains undetermined. In this study, we evaluated the role of IL-17 in ...
IL-27 stimulates human NK-cell effector functions and primes NK cells for IL-18 responsiveness
(Wiley, 2015-01-13)
IL-27, a member of the IL-12 family of cytokines, is produced by APCs, and displays pro- and anti-inflammatory effects. How IL-27 affects human NK cells still remain unknown. In this study, we observed that mature dendritic ...
Regulation of NK cell activation and effector functions by the IL-12 family of cytokines: the case of IL-27
(Frontiers, 2017-01)
Natural killer (NK) cells are characterized by their ability to detect and induce apoptosis of susceptible target cells and by secretion of immunoregulatory cytokines such as IFN-γ. Activation of these effector functions ...
The role of IL-6 on apical periodontitis: a systematic review
(Wiley-Blackwell, 2014-07-01)
The aim of this review was to examine current knowledge of the role of interleukin-6 (IL-6) in apical periodontitis (AP) pathogenesis as an inflammatory or pro-inflammatory cytokine. It also looked at whether IL-6 could ...
Structure and function of interleukin-22 and other members of the interleukin-10 family
(Birkhauser VerlagBasel, 2010-09)
The IL-10 family of cytokines is comprised of IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, and IFN-λs (IL-28A, IL-28B, and IL-29). The IL-10 family members bind to shared class II cytokine receptor chains that associate in ...
CD4+FOXP3+cells produce IL-10 in the spleens of dogs with visceral leishmaniasis
(Elsevier B.V., 2014-05-28)
Visceral Leishmaniasis (VL) is caused by intracellular parasites of the genus Leishmania that affect humans and several animal species. Dogs are one of the main urban reservoirs of the parasite and play a central role in ...