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Adrenal function during childhood and puberty in daughters of women with polycystic ovary syndrome
(Endocrine Society, 2009)
Context: In some patients, PCOS may develop as a consequence of an exaggerated adrenarche during pubertal development. Objective: The aim of the study was to assess adrenal function during childhood and pubertal development ...
Immunoendocrine Interactions during HIV-TB Coinfection: Implications for the Design of New Adjuvant Therapies
(Hindawi Publishing Corporation, 2015-05)
Worldwide, around 14 million individuals are coinfected with both tuberculosis (TB) and human immunodeficiency virus (HIV). In coinfected individuals, both pathogens weaken immunological system synergistically through ...
Adrenal steroids modulate the immune response during Brucella abortus infection by a mechanism that depends on the regulation of cytokine production
(American Society for Microbiology, 2015-05)
Human brucellosis is a protean disease with a diversity of clinical signs and symptoms resulting from infection with Brucella species. Recent reports suggest a cross-regulation between adrenal steroids (cortisol and ...
Anomalías de la esteroidogénesis suprarrenal en niños chilenos con micropene
(Sociedad Médica de Santiago, 2003)
Increased frequency of CD4+ CD25+ FoxP3+ T regulatory cells in pulmonary Tuberculosis patients undergoing specific treatment and its relationship with their immune-endocrine profile
(Hindawi Publishing Corporation, 2015)
Tuberculosis (TB) is a major health problem requiring an appropriate cell immune response (IR) to be controlled. Since regulatory T cells (Tregs) are relevant in IR regulation, we analyzed Tregs variations throughout the ...
Inhibition of Trypanosoma brucei glucose-6-phosphate dehydrogenase by human steroids and their effects on the viability of cultured parasites
(PERGAMON-ELSEVIER SCIENCE LTD, 2009)
Dehydroepiandrosterone ( DHEA) is known as an intermediate in the synthesis of mammalian steroids and a potent uncompetitive inhibitor of mammalian glucose-6-phosphate dehydrogenase (G6PDH), but not the enzyme from plants ...
Dehydroepiandrosterone to induce murine models for the study of Polycystic Ovary Syndrome
(Elsevier, 2010-04)
During the last decade a battery of animal models used for the study of polycystic ovary syndrome (PCOS) have allowed a focus on different aspects of the pathology. Since dehydroepiandrosterone (DHEA) was found to be one ...
Systemic inflammation, cellular influx and up-regulation of ovarian VCAM-1 expression in a mouse model of polycystic ovary syndrome (PCOS)
(Elsevier Ireland, 2011-12)
PCOS, a major cause of anovulatory sterility, is associated with obesity, insulin resistance and chronic inflammation. New evidence suggests that the immune system aggravates the clinical features of PCOS. Our aim was to ...
An adverse immune-endocrine profile in patients with tuberculosis and type 2 diabetes
(Elsevier, 2016-12)
Diabetes is a risk factor for the development of pulmonary tuberculosis (TB) and both diseases present endocrine alterations likely to play a role in certain immuno-endocrine-metabolic associated disorders. Patients with ...