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Óxido nítrico: revisão
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2002-01-01)
O óxido nítrico é um mediador gasoso responsável por uma variedade de fenômenos fisiológicos. A l-arginina é a precursora da síntese do óxido nítrico, na presença de óxido nítrico-sintase. Este artigo revê as funções das ...
Diabetes and Vascular Disease: Basic Concepts of Nitric Oxide Physiology, Endothelial Dysfunction, Oxidative Stress and Therapeutic Possibilities
(BENTHAM SCIENCE PUBL LTD, 2010)
The vascular manifestations associated with diabetes mellitus (DM) result from the dysfunction of several vascular physiology components mainly involving the endothelium, vascular smooth muscle and platelets. It is also ...
Central nifedipine-induced alterations in salivary flow and compounds: Role of nitric oxide
(2006-05-01)
The aim of this study was to examine the role of nifedipine and Nitric Oxide (NO) on salivary flow and compounds (salivary amylase, saliva total proteins, saliva calcium, sodium and potassium). Male Holtzman rats weighting ...
Longitudinal assessment of high versus low levels of fractional exhaled nitric oxide among children with asthma and atopy
(Springer Verlag, 2014)
Fractional exhaled nitric oxide (FeNO) has emerged as an important biomarker in asthma. Increasing evidence points to atopy as a confounding factor in the interpretation of elevated FeNO. We conducted a longitudinal study ...
Myeloperoxidase in Hypertensive Disorders of Pregnancy and Its Relation with Nitric Oxide
(2017-06-01)
Elevated levels of myeloperoxidase have been demonstrated in women with preeclampsia where it may contribute to endothelial dysfunction mediated, in part, by nitric oxide impairment. In this study, we investigated ...
Effects on mitochondria of mitochondria-induced nitric oxide release from a ruthenium nitrosyl complex
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2009)
The ruthenium nitrosyl complex trans-[Ru(NO)(NH(3))(4)(py)](PF(6))(3) (pyNO), a nitric oxide (NO) donor, was studied in regard to the release of NO and its impact both on isolated mitochondria and HepG2 cells. In isolated ...
Retinal cell death induced by TRPV1 activation involves NMDA signaling and upregulation of nitric oxide synthases
(Kluwer Academic/Plenum PublishersNew York, 2013-01-17)
The activation of the transient receptor potential vanilloid type 1 channel (TRPV1) has been correlated with oxidative and nitrosative stress and cell death in the nervous system. Our previous results indicate that TRPV1 ...
A nitric oxide synthase inhibitor decreases 6-hydroxydopamine effects on tyrosine hydroxylase and neuronal nitric oxide synthase in the rat nigrostriatal pathway
(ELSEVIER SCIENCE BV, 2008)
There is evidence that nitric oxide plays a role in the neurotransmitter balance within the basal ganglia and in the pathology of Parkinson`s disease. In the present work we investigated in striatal 6-hydroxydopamine ...