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APC germline mutations in families with familial adenomatous polyposis
(Spandidos Publ LtdAthensGrécia, 2013)
Effects of β-glucan polysaccharide revealed by the dominant lethal assay and micronucleus assays, and reproductive performance of male mice exposed to cyclophosphamide
(Sociedade Brasileira de Genética, 2014)
β-glucan is a well-known polysaccharide for its chemopreventive effect. This study aimed to evaluate the chemopreventive ability of β-glucan in somatic and germ cells through the dominant lethal and micronucleus assays, ...
A polymorphism in the MSH3 mismatch repair gene is associated with the levels of somatic instability of the expanded CTG repeat in the blood DNA of myotonic dystrophy type 1 patients
(2016-04)
Somatic mosaicism of the expanded CTG repeat in myotonic dystrophy type 1 is age-dependent, tissuespecific and expansion-biased, contributing toward the tissue-specificity and progressive nature of the symptoms. Previously, ...
UV-B radiation induces Mu element somatic transposition in maize
(Oxford University Press, 2013-11)
The maize Mutator (MuDR/Mu) transposon family is the most active DNA transposon inplants (Lisch 2002). The Mu family contains diverse elements, all sharing similar ~215 bpterminal inverted repeats (TIRs). MuDR is the ...
Differential expression of genes encoding proteins of the HGF/MET system in insulinomas
(BioMed Central, 2015)
Abstract
Background
Insulinomas are the most common functional pancreatic neuroendocrine tumors, whereas histopathological features do not predict their biological behaviour. ...
Transmissable Dog Cancer Genome Reveals the Origin and History of an Ancient Cell Lineage
(Amer Assoc Advancement Science, 2014-01-24)
Canine transmissible venereal tumor (CTVT) is the oldest known somatic cell lineage. It is a transmissible cancer that propagates naturally in dogs. We sequenced the genomes of two CTVT tumors and found that CTVT has ...
Radioprotection of beta-carotene evaluated on mouse somatic and germ cells
(Elsevier B.V., 1996-09-23)
In the present paper, the protective effect of beta-carotene was evaluated after whole body exposure of mice to 2 Gy of X-rays. Splenocytes, reticulocytes, bone marrow cells and spermatids were evaluated for the frequency ...
Acquired TERT promoter mutations activate TERT expression in mantle cell lymphoma
(John Willey & Sons, 2016-02)
Mantle cell lymphoma (MCL) is an aggressive lymphoid neoplasm with poor prognosis. Acquired telomerasereverse transcriptase gene promoter (TERTp) mutations are among the most frequent somatic non-codingmutations in cancers. ...
Acquired Somatic Mutations In Pnh Reveal Long-term Maintenance Of Adaptive Nk Cells Independent Of Hspcs
(Amer Soc HematologyWashington, 2017)
Metronidazole Induced DNA Damage in Somatic Cells of Drosophila melanogaster
(Bentham Science Publishers, 2013-07)
The standard version of the wing somatic mutation and recombination test (SMART) in Drosophila melanogaster was employed in order to evaluate the genotoxic potential of metronidazole (MTZ) as a function of exposure ...