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Protein misfolding and disease: The case of prion disorders
(2003)
Recent findings strongly support the hypothesis that diverse human disorders, including the most common neurodegenerative diseases, arise from misfolding and aggregation of an underlying protein. Despite the good evidence ...
Amaranth protein films from thermally treated proteins
(Elsevier, 2013-12)
The usefulness of amaranth protein isolates, native and thermally treated, in edible films preparation was studied. Protein films were prepared by casting using glycerol as plasticizer. Films from amaranth native protein ...
Mapping eIF5A binding sites for Dys1 and Lia1: In vivo evidence for regulation of eIF5A hypusination
(2003-12-18)
The evolutionarily conserved factor eIF5A is the only protein known to undergo hypusination, a unique posttranslational modification triggered by deoxyhypusine synthase (Dys1). Although eIF5A is essential for cell viability, ...
Sweet lupin protein quality in young men
(1992)
The protein quality of Lupinus albus cv Multolupa was evaluated in young adult males using the nitrogen balance technique at graded levels of N intake, and compared with egg protein. Lupin protein was consumed at levels ...
Hepatitis C Virus NS2 Protein Inhibits DNA Damage Pathway by Sequestering p53 to the Cytoplasm
(2013-04-30)
Chronic hepatitis C virus (HCV) infection is an important cause of morbidity and mortality globally, and often leads to end-stage liver disease. The DNA damage checkpoint pathway induces cell cycle arrest for repairing DNA ...
An ensemble framework for identifying essential proteins
(2016-08-25)
Background: Many centrality measures have been proposed to mine and characterize the correlations between network topological properties and protein essentiality. However, most of them show limited prediction accuracy, and ...
Biochemical evidence for adhesion-promoting role of major intrinsic protein isolated from both normal and cataractous human lenses
(1995)
In this study, we tested the adhesion-promoting role of major intrinsic protein from both normal human (cadaver) and senile cataractous lenses. Junctional membrane solubilized proteins and pure major intrinsic protein ...