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Influence of Helicobacter pylori infection on the expression of MLH1 and MGMT in patients with chronic gastritis and gastric cancer
(Springer, 2009-06-01)
The aim of the present study was to evaluate the influence of Helicobacter pylori on MLH1 and MGMT mRNA levels in patients with chronic gastritis and gastric cancer. The study included 217 patients, of which 26 were ...
Effects of Helicobacter pylori Infection on the Expressions of Bax and Bcl-2 in Patients with Chronic Gastritis and Gastric Cancer
(Springer, 2010-01-01)
The aim of the present study is to evaluate the influence of Helicobacter pylori on Bax and Bcl-2 mRNA and protein levels in patients with chronic gastritis and gastric cancer. The study included 217 patients, of which 26 ...
DNA mismatch repair gene methylation in gastric cancer in individuals from northern Brazil
(INST HISTOL EMBRIOL-CONICET, 2008)
Gastric cancer is one of the most common malignancies. DNA methylation is implicated in DNA mismatch repair genes deficiency. In the present study, we evaluated the methylation status of MLH1, MSH2, MSH6 and PMS2 in 20 ...
Cytogenetic characterization and evaluation of c-MYC gene amplification in PG100, a new Brazilian gastric cancer cell line
(Associação Brasileira de Divulgação Científica, 2010-08-01)
Gastric cancer is the fourth most frequent type of cancer and the second cause of cancer mortality worldwide. The genetic alterations described so far for gastric carcinomas include amplifications and mutations of the ...
Absence of RKIP expression is an independent prognostic biomarker for gastric cancer patients
(2013-02-01)
Gastric cancer is a leading cause of cancer-related mortality, and the presence of lymph node metastasis an important prognostic factor. Downregulation of RKIP has been associated with tumor progression and metastasis in ...
Inverse expression of survivin and reprimo correlates with poor patient prognosis in gastric cancer
(Impact Journals LLC, 2018)
© Cerda-Opazo et al. BACKGROUND: The objective of the study was to determine the relationship between Survivin and Reprimo transcript/protein expression levels, and gastric cancer outcome. METHODS: In silico correlations ...
Helicobacter pylori infection: Host immune response, implications on gene expression and microRNAs
(Baishideng Publ Grp Co Ltd, 2014-02-14)
Helicobacter pylori (H. pylori) infection is the most common bacterial infection worldwide. Persistent infection of the gastric mucosa leads to inflammatory processes and may remain silent for decades or progress causing ...
Gastric cancer is associated with NOS2-954G/C polymorphism and environmental factors in a Brazilian population
(Biomed Central Ltd., 2010-06-17)
Background: Gastric cancer can progress from a chronic inflammation of the gastric mucosa resulting from Helicobacter pylori infection that activates the inflammatory response of the host. Therefore, polymorphisms in genes ...