Buscar
Mostrando ítems 91-100 de 456
Multivariate discrimination among cryptic mites of the genus Androlaelaps (Acari: Mesostigmata: Laelapidae) parasitic of sympatric akodontine rodents (Cricetidae: Sigmodontinae) in northeastern Argentina: possible evidence of host switch followed by speciation, with the description of two new species
(Springer, 2014-07)
Laelapids are among the most common ectoparasites of rodents. Currently, it is under discussion whether there is a single polixenous species that parasites a variety of hosts, or whether there are cryptic species highly ...
Hepatotoxicity in mice of a novel anti-parasite drug candidate hydroxymethylnitrofurazone: a comparison with Benznidazole
(Public Library Of Science, 2014-10-16)
Hydroxymethylnitrofurazone (NFOH) is a promising drug candidate with demonstrated trypanocidal activity in experimental models ofTrypanosoma cruziinfection and chronic disease development. In this study, we monitored the ...
Synthesis, cytotoxicity and in vitro antileishmanial activity of naphthothiazoles
(2013-06-01)
The leishmaniasis is a spectral disease caused by the protozoan Leishmania spp., which threatens millions of people worldwide. Current treatments exhibit high toxicity, and there is no vaccine available. The need for new ...
Unravelling the Neospora caninum secretome through the secreted fraction (ESA) and quantification of the discharged tachyzoite using high-resolution mass spectrometry-based proteomics
(Biomed Central Ltd., 2013-11-23)
Background: The apicomplexan parasite Neospora caninum causes neosporosis, a disease that leads to abortion or stillbirth in cattle, generating an economic impact on the dairy and beef cattle trade. As an obligatory ...
Cuantificación y evaluación de la estacionalidad de elementos parasitarios en ambientes acuáticos recreativos de la provincia de Salta, ArgentinaQuantification of parasites in aquatic environments in the Province of Salta, Argentina
(Asociación Argentina de Microbiología, 2014-05)
La contaminación microbiológica de aguas recreativas es un problema preocupante, ya que las personas que las utilizan pueden contraer enfermedades que podrían afectar su bienestar general. Para evaluar la calidad del agua, ...
Inhibition by stabilization: Targeting the Plasmodium falciparum aldolase-TRAP complex
(BioMed Central, 2015-08)
Background: Emerging resistance of the malaria parasite Plasmodium to current therapies underscores the critical importance of exploring novel strategies for disease eradication. Plasmodium species are obligate intracellular ...
Amblyomma yucumense n. sp (Acari: Ixodidae), a parasite of wild mammals in Southern Brazil
(Oxford Univ Press Inc, 2015-01-01)
During 2013-2014, adult ticks were collected on the vegetation and subadult ticks were collected from small mammals [Didelphis aurita Wied-Neuwied, Sooretamys angouya (Fischer), Euryoryzomys russatus (Wagner), Akodon ...
Glycosomal Targets for Anti-Trypanosomatid Drug Discovery
(Bentham Science Publ Ltd, 2014-05-01)
Glycosomes are peroxisome-related organelles found in all kinetoplastid protists, including the human pathogenic species of the family Trypanosomatidae: Trypanosoma brucei, Trypanosoma cruzi and Leishmania spp. Glycosomes ...
Glycosomal targets for anti-trypanosomatid drug discovery
(2014-01-01)
Glycosomes are peroxisome-related organelles found in all kinetoplastid protists, including the human pathogenic species of the family Trypanosomatidae: Trypanosoma brucei, Trypanosoma cruzi and Leishmania spp. Glycosomes ...