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Oral health in renal transplant recipients administered cyclosporin A or tacrolimus
(Blackwell Publishing, 2006-05-01)
OBJECTIVE: the aim of this study was to determine the oral status of renal transplant recipients receiving cyclosporin A (CsA) or tacrolimus (FK-506) as immunosuppressant.SUBJECTS AND METHODS: A total of 88 renal transplant ...
Effects of long-term cyclosporin therapy on the periodontium of rats
(2004-08-01)
Background: The treatment of cyclosporin A triggers an early bone loss and gingival overgrowth. There is a lack of studies exploring the effects of long-term cyclosporin A therapy on alveolar bone homeostasis and gingival ...
Effects of cyclosporin, nifedipine and phenytoin on gingival myofibroblast transdifferentiation in monkeys
(Univ Sao Paulo Fac Odontologia Bauru, 2019-01-01)
Objective: Myofibroblasts have been associated with the development of several pathologic fibrotic conditions. This longitudinal study aims to assess the proliferative and antiapoptotic effects of cyclosporin, nifedipine ...
Cyclosporine bioequivalence study: quantification using fluorescence polarization immunoassay (FPIA) and radioimmunoassay (RIA)
(Dustri-verlag Dr Karl FeistleOberhachingAlemanha, 2004)
Influence of age on combined effects of cyclosporin and nifedipine on rat alveolar bone
(2004-02-01)
Background: There is some evidence showing that cyclosporin A (CsA) and nifedipine (NIF) affect bone metabolism. The purpose of this work was to study the effects of CsA and NIF, given alone or concurrently, on alveolar ...
Influence of cyclosporin A on quality of bone around integrated dental implants: a radiographic study in rabbits
(Blackwell Publishing, 2007-02-01)
To evaluate the influence of cyclosporin A (CsA) administration on bone around integrated dental implants assessed by a bone quality index and by quantitative subtraction radiography.A total of 36 machine surface commercial ...
Cyclosporin but not tacrolimus significantly increases salivary cytokine contents in rats
(2005-09-01)
Background: Cyclosporin (CsA) and tacrolimus (FK-506) are immunosuppressive drugs that specifically inhibit T-cell activation via calcineurin inhibition. Gingival overgrowth is a common side effect following the administration ...
Cyclosporine A – Induced gingival overgrowth and proliferating cell nuclear antigen expression in experimental periodontitis
(2019-01-01)
The most important microscopic characteristic of Cyclosporine A-induced gingival overgrowth is fibroepithelial hyperplasia. Objective: The objective was to investigate the influence of previous exposure to Cyclosporine A ...