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Pathological and biochemical changes induced in mice after intramuscular injection of venom from newborn specimens of the snake Bothrops asper (Terciopelo)
(1992-09)
Venom from newborn Bothrops asper snakes has higher lethal, hemorrhagic, edema-forming, proteolytic and defibrinating activities than venom from adult B. asper specimens. Electrophoretic analysis confirmed the variation ...
Skeletal muscle necrosis and regeneration after injection of Thalassophryne nattereri (niquim) fish venom in mice
(2001-02)
Stings by Thalassophryne nattereri are responsible for envenomation of fishermen in north-eastern Brazil. Its venom induces prominent local tissue damage, characterized by pain, oedema and necrosis. The pathogenesis of ...
Skin Pathology Induced by Snake Venom Metalloproteinase: Acute Damage, Revascularization, and Re-epithelization in a Mouse Ear Model
(2008-10)
Viperid snakebite envenomation induces blistering and dermonecrosis. The pathological alterations induced by a snake venom metalloproteinase in the skin were investigated in a mouse ear model. Metalloproteinase BaP1, from ...
Effects of Bothrops asper (terciopelo) myotoxin III, a basic phospholipase A2, on liposomes and mouse gastrocnemius muscle
(1993-02)
The action of Bothrops asper myotoxin III, a basic phospholipase A2 which induces acute muscle damage, was studied in mouse gastrocnemius muscle in vivo and in vitro and in multilamellar liposomes. Myonecrosis occurred ...
Tissue Inhibitor of Metalloproteinase-1 Is Confined to Tumor-Associated Myofibroblasts and Is Increased With Progression in Gastric Adenocarcinoma
(2016)
The tissue inhibitor of metalloproteinase-1 (TIMP-1) inhibits the extracellular matrix–degrading activity of several matrix metalloproteinases, thereby regulating cancer cell invasion and metastasis. Studies describing the ...
Skeletal muscle degeneration and regeneration after injection of bothropstoxin-II, a phospholipase A2 isolated from the venom of the snake Bothrops jararacussu
(1991)
A myotoxic phospholipase A2, named bothropstoxin II (BthTX-II), was isolated from the venom of the South American snake Bothrops jararacussu and the pathogenesis of myonecrosis induced by this toxin was studied in mice. ...
Neutrophils do not contribute to local tissue damage, but play a key role in skeletal muscle regeneration, in mice injected with Bothrops asper snake venom
(2003-10)
Local tissue damage induced by crotaline snake venoms includes edema, myonecrosis, hemorrhage, and an inflammatory response associated with a prominent cellular infiltrate. The role of neutrophils in the local tissue damage ...
Valor diagnóstico de anticuerpos anti Helicobacter pylori en pacientes referidos al Servicio de Endoscopía Digestiva del Hospital San Vicente de Paul, Costa Rica
(Novel Mutations in the MYOC/GLC1A Gene in a Large Group of Glaucoma Patients Hum Mutat 20 (6) 479-484, 2002)
Antibodies titers against H. pylori antigens were determined in 78 patients referred to the Digestive Endoscopy Service of the San Vicente de Paul Hospital, Costa Rica. The assay was performed by enzyme immunoassay (ELISA), ...
Asociación del polimorfismo del codon 72 del gen P53 con el riesgo de cáncer gástrico en una población de alto riesgo de Costa Rica
(Revista de Biología Tropical 53 (3-4): 317-324, 2005, 2005-10-03)
El cáncer gástrico es la segunda causa de muerte por cáncer en el mundo. Varios factores han sido asociados con el riesgo de llegar a desarrollarlo, entre ellos la predisposición genética. El gen p53 presenta un polimorfismo ...
Fasciola hepatica en ganado bovino de carne en Siquirres y lesiones anatomo-histopatológicas de hígados bovinos decomisados en mataderos de Costa Rica
(2013-12-11)
This study was carried out in order to determine Fasciola hepatica infection in a farm dedicated to fattening beef cattle in Siquirres, Limón province; also, to characterize the most common lesions in parasitized bovine ...