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Identification, recombinant production and partial biochemical characterization of an extracellular cold-active serine-metalloprotease from an Antarctic Pseudomonas isolate
(AIMS Press, 2017)
Cold-adapted enzymes are generally derived from psychrophilic microorganisms and have features that make them very attractive for industrial and biotechnological purposes. In this work, we identified a 50 kDa extracellular ...
Galectin-8 mediates fibrogenesis induced by cyclosporine in human gingival fibroblasts
(2020-10-01)
Background and Objective: During cyclosporine-induced gingival overgrowth, the homeostatic balance of gingival connective tissue is disrupted leading to fibrosis. Galectins are glycan-binding proteins that can modulate a ...
Truncated hantavirus nucleocapsid proteins for serotyping Sin Nombre, Andes, and Laguna Negra hantavirus infections in humans and rodents
(American Society for Microbiology, 2013)
Truncated hantavirus nucleocapsid proteins for serotyping Sin Nombre, Andes, and Laguna Negra hantavirus infections in humans and rodents
(American Society for Microbiology, 2013)
5α-reductase type 3 enzyme in benign and malignant prostate
(2014-02)
BACKGROUND Currently available 5α-reductase inhibitors are not completely effective for treatment of benign prostate enlargement, prevention of prostate cancer (CaP), or treatment of advanced castration-recurrent (CR) CaP. ...
An essential thioredoxin-type protein of Trypanosoma brucei acts as redox-regulated mitochondrial chaperone
(Public Library of Science, 2019)
Most known thioredoxin-type proteins (Trx) participate in redox pathways, using two highly conserved cysteine residues to catalyze thiol-disulfide exchange reactions. Here we demonstrate that the so far unexplored Trx2 ...
Efecto de lisina y ácido glutámico en la purificación de la proteína GPN2 humana expresada en E. coli
(Universidad Autónoma Metropolitana (México). Unidad Azcapotzalco. División de Ciencias Básicas e Ingeniería., 2017)
La proteína humana GPN2 participa en la biogénesis de la RNA polimerasa II, se expresó como proteína recombinante en E. coli y se purificó por cromatografía por afinidad por metales inmovilizados en níquel (IMAC, por sus ...