dc.creatorMartín-Cruces, José
dc.creatorCuendias, Patricia
dc.creatorGarcía-Mesa, Yolanda
dc.creatorCobo, Juan L.
dc.creatorGarcía-Suárez, Olivia
dc.creatorGaite, Juan J.
dc.creatorVega, José A.
dc.creatorMartín-Biedma, Benjamín
dc.date2024-04-09T22:57:49Z
dc.date2024-04-09T22:57:49Z
dc.date2024
dc.date.accessioned2024-07-17T21:13:53Z
dc.date.available2024-07-17T21:13:53Z
dc.identifier10.1002/ar.25324
dc.identifier19328486
dc.identifierhttps://hdl.handle.net/20.500.12728/10327
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9509577
dc.descriptionThe objective of this study was to analyze the proprioceptive innervation of human lips, especially of the orbicularis oris muscle, since it is classically accepted that facial muscles lack typical proprioceptors, that is, muscle spindles, but recently this has been doubted. Upper and lower human lips (n = 5) from non-embalmed frozen cadavers were immunostained for detection of S100 protein (to identify nerves and sensory nerve formations), myosin heavy chain (to label muscle fibers within muscle spindles), and the mechano-gated ion channel PIEZO2. No muscle spindles were found, but there was a high density of sensory nerve formations, which were morphologically heterogeneous, and in some cases resemble Ruffini-like and Pacinian sensory corpuscles. The axons of these sensory formations displayed immunoreactivity for PIEZO2. Human lip muscles lack typical proprioceptors but possess a dense sensory innervation which can serve the lip proprioception. © 2023 The Authors. The Anatomical Record published by Wiley Periodicals LLC on behalf of American Association for Anatomy.
dc.descriptionFUO; Marta Sánchez-Pitiot; Universidad de Oviedo
dc.formatapplication/pdf
dc.languageen
dc.publisherJohn Wiley and Sons Inc
dc.subjecthuman lips
dc.subjectmechano-gated ion channels
dc.subjectproprioception
dc.subjectsensory nerve formations
dc.titleProprioceptive innervation of the human lips
dc.typeArticle


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