Survival of osseointegrated implants in head and neck cancer patients submitted to multimodal treatment: a systematic review and meta-analysis

dc.creatorCamolesi, Gisela Cristina Vianna
dc.creatorVeronese, Henrique Rocha Mazorchi
dc.creatorCelestino, Miriã Andrade
dc.creatorBlum, Davi Francisco Casa
dc.creatorMárquez-Zambrano, José Agustín
dc.creatorCarmona-Pérez, Francisca Andrea
dc.creatorJara-Venegas, Tamara Andrea
dc.creatorPellizzon, Antonio Cassio Assis
dc.creatorBernaola-Paredes, Wilber Edison
dc.date2024-04-12T06:26:35Z
dc.date2024-04-12T06:26:35Z
dc.date2023
dc.date.accessioned2024-07-17T21:10:50Z
dc.date.available2024-07-17T21:10:50Z
dc.identifier10.1007/s00520-023-08088-5
dc.identifier09414355
dc.identifierhttps://hdl.handle.net/20.500.12728/11181
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9508971
dc.descriptionPurpose: To investigate the survival rate in implants placement in irradiated and non-irradiated bone in patients undergoing head and neck cancer (HNC) treatment. We focused on the consequences of the main complications, such as osteoradionecrosis and peri-implantitis. Methods: An electronic search conducted by PRISMA protocol was performed. Full texts were carefully assessed, and data were assimilated into a tabular form for discussion and consensus among the expert panel. The quality assessment and the risk of bias are verified by Joanna Briggs Institute checklist (JBI) and The Newcastle–Ottawa Scale (NOS), and Risk of Bias in Non-Randomized Studies of Interventions (ROBINS-I) assessment tool. Results: A total of 452 records were identified in the based on our PICOs strategy and after screening, 19 articles were included in the descriptive analysis of the review. Totaling 473 implants placed in irradiated and non-irradiated bone, and 31.6% of the patients were over 60 years of age. 57.9%) performed implant placement in a period of 12 months or more after the ending of radiotherapy. Only 5 studies had a follow-up period longer than 5 years after implant placement, of which three were used for the meta-analysis. In the meta-analysis of 5-year survival rate, analysis of implants in irradiated bone was assessed; a random effect model was used and a weighted proportion (PP) of 93.13% (95% CI: 87.20–99.06; p < 0.001), and in the 5-year survival rate, analysis of implants in non-irradiated bone was analysed; a fixed effect model was used and a weighted proportion (PP) of 98.52% survival (95% CI: 97.56–99.48, p < 0.001). Conclusions: Survival rates of implants placed in irradiated bone are clinically satisfactory after a follow-up of 5 years, with a fewer percentage than in implants placed in non-irradiated bone after metanalyses performed. © 2023, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
dc.formatapplication/pdf
dc.languageen
dc.publisherSpringer Science and Business Media Deutschland GmbH
dc.subjectCancer of head and neck
dc.subjectDental implants
dc.subjectIntensity-modulated radiotherapy
dc.subjectMandibular reconstruction
dc.subjectOral surgical procedures
dc.subjectSurvival implants
dc.titleSurvival of osseointegrated implants in head and neck cancer patients submitted to multimodal treatment: a systematic review and meta-analysis
dc.typeArticle


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