The role of regulatory T cells and follicular T helper cells in HBV infection
| dc.creator | Lin, Nengqi | |
| dc.creator | Yin, Wei | |
| dc.creator | Miller, Heather | |
| dc.creator | Byazrova, Maria G. | |
| dc.creator | Herrada, Andrés A. | |
| dc.creator | Benlagha, Kamel | |
| dc.creator | Lee, Pamela | |
| dc.creator | Guan, Fei | |
| dc.creator | Lei, Jiahui | |
| dc.creator | Gong, Quan | |
| dc.creator | Yan, Youqing | |
| dc.creator | Filatov, Alexander | |
| dc.creator | Liu, Chaohong | |
| dc.date | 2024-04-10T00:45:18Z | |
| dc.date | 2024-04-10T00:45:18Z | |
| dc.date | 2023 | |
| dc.date.accessioned | 2024-07-17T21:10:21Z | |
| dc.date.available | 2024-07-17T21:10:21Z | |
| dc.identifier | 10.3389/fimmu.2023.1169601 | |
| dc.identifier | 16643224 | |
| dc.identifier | https://hdl.handle.net/20.500.12728/10509 | |
| dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/9508851 | |
| dc.description | Hepatitis B has become one of the major global health threats, especially in developing countries and regions. Hepatitis B virus infection greatly increases the risk for liver diseases such as cirrhosis and cancer. However, treatment for hepatitis B is limited when considering the huge base of infected people. The immune response against hepatitis B is mediated mainly by CD8+ T cells, which are key to fighting invading viruses, while regulatory T cells prevent overreaction of the immune response process. Additionally, follicular T helper cells play a key role in B-cell activation, proliferation, differentiation, and formation of germinal centers. The pathogenic process of hepatitis B virus is generally the result of a disorder or dysfunction of the immune system. Therefore, we present in this review the critical functions and related biological processes of regulatory T cells and follicular T helper cells during HBV infection. Copyright © 2023 Lin, Yin, Miller, Byazrova, Herrada, Benlagha, Lee, Guan, Lei, Gong, Yan, Filatov and Liu. | |
| dc.format | application/pdf | |
| dc.language | en | |
| dc.publisher | Frontiers Media S.A. | |
| dc.subject | follicular T helper cell | |
| dc.subject | HBV | |
| dc.subject | infection | |
| dc.subject | potential therapy | |
| dc.subject | regulatory T cell | |
| dc.title | The role of regulatory T cells and follicular T helper cells in HBV infection | |
| dc.type | Article |