A global metagenomic map of urban microbiomes and antimicrobial resistance

dc.creatorDanko, D; Bezdan, D., Afshin, EE.; Ahsanuddin, Sofia; Bhattacharya, Chandrima; Butler, Daniel J.; Chng, Kern Rei; Donnellan, Daisy; Hecht, Jochen; Jackson, Katelyn; Kuchin, Katerina ; Karasikov, Mikhail; Lyons, Abigail; Mak, Lauren; Meleshko, Dmitry; Mustafa, Harun; Mutai, Beth; Neches, Russell Y.; Ng, Amanda; Nikolayeva, Olga; Nikolayeva, Tatyana; Png, Eileen; Ryon, Krista A.; Sanchez, Jorge L.; Shaaban, Heba; Sierra, Maria A.; Thomas, Dominique; Young, Ben; Abudayyeh, Omar O.; Alicea, Josue; Bhattacharyya, Malay; Blekhman, Ran; Castro-Nallar, Eduardo; Cañas, Ana M.; Chatziefthimiou, Aspassia D.; Crawford, Robert W.; De Filippis, Francesca; Deng, Youping; Desnues, Christelle; Dias-Neto, Emmanuel; Dybwad, Marius; Elhaik, Eran; Ercolini, Danilo; Frolova, Alina; Gankin, Dennis; Gootenberg, Jonathan S.; Graf, Alexandra B.; Green, David C.; Hajirasouliha, Iman; Hastings, Jaden J. A.; Hernandez, Mark; Jang, Soojin; Kahles, Andre; Kelly, Frank J.; Knights, Kaymisha; Kyrpides, Nikos C.; Labaj, Pawel P.; Lee, Patrick K. H.; Leung, Marcus H. Y.; Ljungdahl, Per O.; Mason-Buck, Gabriella; McGrath, Ken; Meydan, Cem; Mongodin, Emmanuel F.; Moraes, Milton Ozorio; Nagarajan, Niranjan; Nieto-Caballero, Marina; Noushmehr, Houtan; Oliveira, Manuela; Ossowski, Stephan; Osuolale, Olayinka O.; Ozcan, Orhan; Paez-Espino, David; Rascovan, Nicolas; Richard, Hugues; Ratsch, Gunnar; Schriml, Lynn M.; Semmler, Torsten; Sezerman, Osman U; Shi, Leming; Shi, Tieliu; Siam, Rania; Song, Le Huu ; Suzuki, Haruo; Court, Denise Syndercombe; Tighe, Scott W.; Tong, Xinzhao;Udekwu, Klas, I; Ugalde, Juan A.; Valentine, Brandon; Vassilev, Dimitar, I; Vayndorf, Elena M.; Velavan, Thirumalaisamy P.; Wu, Ju; Zambrano, Maria M. ; Zhu, Jifeng; Zhu, Sibo; Mason, Christopher E.
dc.creatorIraola, Gregorio [Univ Mayor, Ctr Integrat Biol, Chile]
dc.date.accessioned2023-12-28T14:52:05Z
dc.date.accessioned2024-05-02T20:50:20Z
dc.date.available2023-12-28T14:52:05Z
dc.date.available2024-05-02T20:50:20Z
dc.date.created2023-12-28T14:52:05Z
dc.date.issued2021-06-24
dc.identifierDanko, D., Bezdan, D., Afshin, E. E., Ahsanuddin, S., Bhattacharya, C., Butler, D. J., ... & Black, C. (2021). A global metagenomic map of urban microbiomes and antimicrobial resistance. Cell, 184(13), 3376-3393.
dc.identifier0092-8674
dc.identifiereISSN 1097-4172
dc.identifierWOS: 000665547300006
dc.identifierPMID: 34043940
dc.identifierhttps://repositorio.umayor.cl/xmlui/handle/sibum/9182
dc.identifierhttps://escholarship.org/content/qt6x297461/qt6x297461.pdf
dc.identifierhttps://amu.hal.science/hal-03357730/file/1-s2.0-S0092867421005857-main.pdf
dc.identifierhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238498/?report=reader
dc.identifierhttps://doi.org/10.1016%2Fj.cell.2021.05.002
dc.identifierhttps://pub.epsilon.slu.se/25006/1/danko_d_ety_al_210824.pdf
dc.identifierhttps://amu.hal.science/hal-03357730/document
dc.identifierhttps://escholarship.org/content/qt6x297461/qt6x297461.pdf?t=qxz7y9
dc.identifierhttps://www.zora.uzh.ch/id/eprint/210801/1/PIIS0092867421005857.pdf
dc.identifierhttps://amu.hal.science/hal-03357730/document
dc.identifierhttps://doi-org.bibliotecadigital.umayor.cl:2443/10.1016/j.cell.2021.05.002
dc.identifier10.1016/j.cell.2021.05.002
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9275967
dc.description.abstractWe present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60 cities over 3 years, representing the first systematic, worldwide catalog of the urban microbial ecosystem. This atlas provides an annotated, geospatial profile of microbial strains, functional characteristics, antimicrobial resistance (AMR) markers, and genetic elements, including 10,928 viruses, 1,302 bacteria, 2 archaea, and 838,532 CRISPR arrays not found in reference databases. We identified 4,246 known species of urban microorganisms and a consistent set of 31 species found in 97% of samples that were distinct from human commensal organisms. Profiles of AMR genes varied widely in type and density across cities. Cities showed distinct microbial taxonomic signatures that were driven by climate and geographic differences. These results constitute a high-resolution global metagenomic atlas that enables discovery of organisms and genes, highlights potential public health and forensic applications, and provides a culture-independent view of AMR burden in cities.
dc.languageen_US
dc.publisherCELL PRESS
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
dc.titleA global metagenomic map of urban microbiomes and antimicrobial resistance
dc.typeArtículo o Paper


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