Chitosan-pluronic based Cu nanocomposite hydrogels for prototype antimicrobial applications

dc.creatorJayaramudu, Tippabattini
dc.creatorVaraprasad, Kokkarachedu
dc.creatorReddy, K. Koteshwara
dc.creatorPyarasani, Radha D.
dc.creatorAkbari-Fakhrabadi, A.
dc.creatorAmalraj, John
dc.date2023-05-02T19:07:36Z
dc.date2023-05-02T19:07:36Z
dc.date2020
dc.date.accessioned2024-05-02T20:31:09Z
dc.date.available2024-05-02T20:31:09Z
dc.identifierhttp://repositorio.ucm.cl/handle/ucm/4737
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9274975
dc.descriptionCopper nanoparticles were synthesized via precipitation technique using the pseudonatural cationic chitosan biopolymer as a stabilizing agent. The nanoparticles developed were successfully incorporated into the 1:1 ratio of blended chitosan: pluronic F127 polymer solution and made their nanocomposite hydrogels by solution casting method. The formed copper-based nanocomposite hydrogels were characterized by using Fourier transform infrared spectroscopy, thermogravimetric analysis, X-ray diffraction, scanning electron microscopy-energy dispersive spectroscopy and transmission electron microscopy studies. The antimicrobial activity of the fabricated nanocomposite hydrogels was tested via an inhibition zone process against both E. coli (gram-negative) and S. aureus (gram-positive) bacteria. The results conveyed that the copper-embedded chitosan-pluronic\ F127 nanocomposite hydrogels can be used effectively for antimicrobial applications as well as for wound care applications.
dc.languageen
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 Chile
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
dc.sourceInternational Journal of Biological Macromolecules, 143, 825-832
dc.subjectChitosan
dc.subjectCopper nanoparticles
dc.subjectNanocomposite hydrogels
dc.titleChitosan-pluronic based Cu nanocomposite hydrogels for prototype antimicrobial applications
dc.typeArticle


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