dc.creatorLanderos, Natalia
dc.creatorDuk, Soledad
dc.creatorMárquez, Carolina
dc.creatorInzunza, Bárbara
dc.creatorAcuña-Rodríguez, Ian S.
dc.creatorZúñiga-Venegas, Liliana A.
dc.date2023-01-20T12:22:01Z
dc.date2023-01-20T12:22:01Z
dc.date2022
dc.date.accessioned2024-05-02T20:30:26Z
dc.date.available2024-05-02T20:30:26Z
dc.identifierhttp://repositorio.ucm.cl/handle/ucm/4399
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9274644
dc.descriptionSignificant risks to human health have been associated with chronic exposure to low doses of pesticides, a situation which may be frequent among agricultural workers. In this context, and regarding the agricultural-based economy of central Chile, we aimed to explore the genotoxic damage in agricultural workers and reproductive risk among women in rural and urban areas of Curicó, a traditional agricultural district in Chile. Hence, we sampled a group of rural agricultural workers associated with pesticide management (n = 30) and an urban unexposed group (n = 30). Our results showed that the agricultural workers had higher micronuclei frequencies (MN: β = 13.27; 95% CI low = 11.08, CI high = 15.47) and women had a 40-fold higher risk of reproductive problems (OR = 40.32; 95% CI low = 2.60, CI high = 624.31) than the unexposed group. The factor analysis of mixed data (FAMD) showed that neither the sex nor smoking habits appear to define the ordination of the data. Nevertheless, the exposure level did segregate them in the multidimensional space (explained variance: 35.38% dim-1; 18.63% dim-2). This pilot study highlights the higher risks of biological conditions negatively associated with the health of agricultural workers.
dc.languageen
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 Chile
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
dc.sourceInternational Journal of Environmental Research and Public Health, 19(24), 16608
dc.subjectGenotoxicity
dc.subjectReproductive risk
dc.subjectAgricultural workers
dc.subjectPesticide exposure
dc.subjectChile
dc.titleGenotoxicity and reproductive risk in workers exposed to pesticides in rural areas of Curicó, Chile: a pilot study
dc.typeArticle


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