Prevalence of plasmid-mediated quinolone resistance determinant aac(6 ')-Ib-cr among ESBL producing enterobacteria isolates from Chilean hospitals

dc.creatorElgorriaga Islas, Eliu
dc.creatorGuggiana Nilo, Piero
dc.creatorDominguez Yevenes, Mariana
dc.creatorGonzalez Rocha, Gerardo
dc.creatorMella Montecinos, Sergio
dc.creatorLabarca Labarca, Jaime
dc.creatorGarcia Canete, Patricia
dc.creatorBello Toledo, Helia
dc.date.accessioned2024-01-10T12:41:44Z
dc.date.accessioned2024-05-02T18:51:41Z
dc.date.available2024-01-10T12:41:44Z
dc.date.available2024-05-02T18:51:41Z
dc.date.created2024-01-10T12:41:44Z
dc.date.issued2012
dc.identifier10.1016/j.eimc.2012.01.024
dc.identifier1578-1852
dc.identifier0213-005X
dc.identifierMEDLINE:22542083
dc.identifierhttps://doi.org/10.1016/j.eimc.2012.01.024
dc.identifierhttps://repositorio.uc.cl/handle/11534/77446
dc.identifierWOS:000310092900008
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9271366
dc.description.abstractIntroduction: The frequency of aac(6')-Ib-cr gene in ESBL-producing strains of Klebsiella pneumoniae and Escherichia coli is unknown, in Chile.
dc.description.abstractMethodology: The aac(6')-Ib and aac(6')-Ib-cr genes were investigated using polymerase chain reaction (PCR), restriction fragment length polymorphism (RFLP), and sequencing, in strains isolated from 10 Chilean hospitals between 2008-2009.
dc.description.abstractResults: The aac(6')-Ib-cr gene was detected in 54% of K. pneumoniae and 74% of E. coli strains. The CIM50 of CIP was higher among strains harboring aac(6')-Ib-cr, 8 times higher in K. pneumoniae and 4 times higher in E. coli. Moreover, both aac(6')-Ib and aac(6')-Ib-cr were simultaneously found in 13 K. pneumoniae and 3 E. coli isolates.
dc.description.abstractConclusion: This is the first report of aac(6')-Ib-cr in ESBL-producing strains of K. pneumoniae and E. coli isolated from in-patients in Chilean hospitals located along an area of more than 2,800 Km. (C) 2011 Elsevier Espana, S.L. All rights reserved.
dc.languagees
dc.publisherEDICIONES DOYMA S A
dc.rightsacceso restringido
dc.subjectaac(6 ')-Ib
dc.subjectaac(6 ')-Ib-cr
dc.subjectKlebsiella pneumoniae
dc.subjectEscherichia coli
dc.subjectPlasmid-Mediated Quinolone Resistance (PMQR)
dc.subjectQuinolone
dc.subjectChile
dc.subjectCIPROFLOXACIN
dc.titlePrevalence of plasmid-mediated quinolone resistance determinant aac(6 ')-Ib-cr among ESBL producing enterobacteria isolates from Chilean hospitals
dc.typeartículo


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