dc.creator | Morgado Ahumada, Álvaro Esteban | |
dc.creator | Köhnenkampf, Ruth | |
dc.creator | Balcells Marty, María Elvira | |
dc.creator | Navarrete, Pablo | |
dc.creator | García Cañete, Patricia Del Carmen | |
dc.date.accessioned | 2023-11-10T19:27:00Z | |
dc.date.accessioned | 2024-05-02T17:35:40Z | |
dc.date.available | 2023-11-10T19:27:00Z | |
dc.date.available | 2024-05-02T17:35:40Z | |
dc.date.created | 2023-11-10T19:27:00Z | |
dc.date.issued | 2012 | |
dc.identifier | 10.4067/S0034-98872012000700004 | |
dc.identifier | 0034-9887 | |
dc.identifier | PUBMED_ID: 23282696 | |
dc.identifier | SCOPUS_ID: 84868334571 | |
dc.identifier | http://www.scielo.cl/pdf/rmc/v140n7/art04.pdf | |
dc.identifier | https://repositorio.uc.cl/handle/11534/75295 | |
dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/9268575 | |
dc.description.abstract | Background: The incidence and epidemiological profile of tuberculosis (TB) has changed significantly in the recent years in Chile. Aim: To evaluate the clinical and epidemiological characteristics of TB cases diagnosed in the last decade at a university hospital in Santiago. Material and Methods: The Mycobacterium tuberculosis culture registry of the microbiology laboratory was reviewed. Medical records of patients with a positive culture registered between 2000 and 2010 were retrieved and analyzed. Results: Two hundred forty positive Mycobacterium tuberculosis cultures were identified and the medical records of 158 of these patients were accessed for analysis. The median age was 53 years (range: 3 to 89), 55.1% were female and nearly 42% had extra-pulmonary TB. Among known risk factors, 32.9% of patients were older than 65 years, 4.4% were health care workers and 3.9% immigrants. Twenty eight percent (41/145) had some type of immunosuppression at diagnosis: 11.7% HIV infection and 16.6% were using immunosuppressive drugs. In this group, a previous tuberculin skin test was done in only 5 cases (12.2%). Adverse events related to TB treatment were reported in 21.3% of cases (17/80). No cases of fulminant hepatitis or death from this cause were identified. Four of 92 patients that had a complete follow up during treatment, died. Two of these patients were receiving steroids. Conclusions: Almost one third of TB cases occurred among immunosuppressed patients and 42% were extra-pulmonary forms. The prevention of TB reactivation in this group should be strengthened. | |
dc.language | es | |
dc.rights | acceso abierto | |
dc.subject | Immunosuppression | |
dc.subject | Myocbacterium tuberculosis | |
dc.subject | Risk factors | |
dc.subject | Tuberculosis | |
dc.title | Perfil clínico y epidemiológico de los casos de tuberculosis atendidos en una red de salud universitaria en Santiago de Chile entre los años 2000-2010 | |
dc.type | artículo | |