Morinda citrifolia linn leaf extract possesses antioxidant activities and reduces nociceptive behavior and leukocyte migration

dc.creatorSerafini, Mairim Russo
dc.creatorSantos, Rodrigo Correia
dc.creatorGuimarães, Adriana Gibara
dc.creatorSantos, João Paulo Almeida dos
dc.creatorSantos, Alan Diego da Conceição
dc.creatorAlves, Izabel Almeida
dc.creatorGelain, Daniel Pens
dc.creatorNogueira, Paulo Cesar de Lima
dc.creatorQuintans-Júnior, Lucindo José
dc.creatorBonjardim, Leonardo Rigoldi
dc.creatorAraújo, Adriano Antunes de Souza
dc.date2013-06-08T00:00:38Z
dc.date2013-06-08T00:00:38Z
dc.date2011-10
dc.date.accessioned2023-09-28T22:52:00Z
dc.date.available2023-09-28T22:52:00Z
dc.identifierSERAFINI, M. R. et al. Morinda citrifolia linn leaf extract possesses antioxidant activities and reduces nociceptive behavior and leukocyte migration. Journal of Medicinal Food, San Diego, v. 14, n. 10, out. 2011. Disponível em: <http://online.liebertpub.com/doi/abs/10.1089/jmf.2010.0254>. Acesso em: 7 jun. 2013.
dc.identifier1557-7600
dc.identifierhttps://ri.ufs.br/handle/riufs/594
dc.identifierCopyright Mary Ann Liebert, Inc.
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9079761
dc.descriptionThis is a copy of an article published in the Journal of Medicinal Food© 2011 - copyright Mary Ann Liebert, Inc.; Journal of Medicinal Food is available online at: http://online.liebertpub.com
dc.descriptionHerbal drugs have been used since ancient times to treat a wide range of diseases. Morinda citrifolia Linn (popularly known as ‘‘Noni’’) has been used in folk medicine by Polynesians for over 2,000 years. It is reported to have a broad range of therapeutic effects, including effects against headache, fever, arthritis, gingivitis, respiratory disorders, infections, tuberculosis, and diabetes. The aim of this study was to investigate the antioxidant, anti-inflammatory, antinociceptive, and antibacterial properties of the aqueous extract from M. citrifolia leaves (AEMC). Antioxidant activity was observed against lipid peroxidation, nitric oxide, and hydroxyl radicals. The antinociceptive effect of AEMC was observed in the acetic acid–induced writhing test at the higher dose. Moreover, AEMC significantly reduced the leukocyte migration in doses of 200 and 400 mg/kg and showed mild antibacterial activity. Together, the results suggest that properties of M. citrifolia leaf extract should be explored further in order to achieve newer tools for managing painful and inflammation conditions, including those related to oxidant states.
dc.formatapplication/pdf
dc.languageen
dc.publisherMary Ann Liebert, Inc.
dc.subjectAnti-inflamatório
dc.subjectAtividade antinociceptiva
dc.subjectAtividade antioxidante
dc.subjectMorinda citrifolia
dc.titleMorinda citrifolia linn leaf extract possesses antioxidant activities and reduces nociceptive behavior and leukocyte migration
dc.typeArtigo


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