Effect of periodontal therapy on metabolic control and levels of IL-6 in the gingival crevicular fluid in type 2 diabetes mellitus

dc.creatorCamargo, Gabriela Alessandra da Cruz Galhardo
dc.creatorLima, Meyriane de Andrade
dc.creatorFortes, Tânia Vieira
dc.creatorSouza, Cristiane Salgado de
dc.creatorJesus, Amélia Maria Ribeiro de
dc.creatorAlmeida, Roque Pacheco de
dc.date2014-02-22T00:17:13Z
dc.date2014-02-22T00:17:13Z
dc.date2013-07
dc.date.accessioned2023-09-28T22:47:25Z
dc.date.available2023-09-28T22:47:25Z
dc.identifierCAMARGO, G. A. C. G. et al. Effect of periodontal therapy on metabolic control and levels of IL-6 in the gingival crevicular fluid in type 2 diabetes mellitus. Indian Journal of Dental Research, New Delhi, v. 24, n. 1, 2013. Disponível em: <http://www.ijdr.in/text.asp?2013/24/1/110/114953>. Acesso em: 21 fev. 2014.
dc.identifier1998-3603
dc.identifierhttps://ri.ufs.br/handle/riufs/937
dc.identifierCreative Commons Attribution 3.0 Unported License
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9077983
dc.descriptionBackground: The aim of this study was to compare the efficacy of metabolic control and levels of interleukin 6 (IL-6) in gingival crevicular fluid after periodontal therapy in type 2 diabetes mellitus (DM) and nondiabetic (NDM) patients. Methods: This study was performed in 20 subjects (10 type 2 DM and 10 NDM patients with generalized chronic periodontal disease. Both groups were recorded for clinical parameters (plaque index (PI), gingival index (GI), probing depth (PD), gingival recession (GR) and clinical attachment level (CAL)), metabolic control (fasting glucose levels, glycated a-hemoglobin (HbA1c), low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglycerides (TR)), and IL-6 levels at baseline and 3 months after periodontal treatment. Results: DM and NDM patients revealed significant statistical reductions for clinical parameters (P < 0.05, RM ANOVA) after 3 months. DM group had improvements on HbA1c and had significant statistical increased of TRG (P < 0.05, RM ANOVA) after 3 months. No differences of LDL/HDL and IL-6 levels were found after 3 months in both groups. Conclusion: DM group presented a significant reduction of HbA1c levels after periodontal therapy. However, TRG levels increased after 3 months, which suggest more confirmatory studies to investigate if these results will be repeated in other studies.
dc.formatapplication/pdf
dc.languageen
dc.publisherMedknow
dc.subjectTerapia periodontal
dc.subjectDiabetes mellitus tipo 2
dc.subjectInterleucina
dc.subjectDoença periodontal
dc.titleEffect of periodontal therapy on metabolic control and levels of IL-6 in the gingival crevicular fluid in type 2 diabetes mellitus
dc.typeArtigo


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