Artigo de Periódico
Draft genome sequences of two species of “difficult-to-identify” human-pathogenic corynebacteria: implications for better identification tests.
Registro en:
1839-9940
10.7150/jgen.12886
Autor
PACHECO, Luis Gustavo Carvalho
GUARALDI, Ana Luiza de Mattos
SANTOS, Carolina Silva
VERAS, Adonney Allan de Oliveira
GUIMARÃES, Luís Carlos
ABREU, Vinicius Augusto Carvalho de
PEREIRA, Felipe Luiz
SOARES, Siomar de Castro
DORELLA, Fernanda Alves
CARVALHO, Alex Fiorini de
LEAL, Carlos Augusto Gomes
FIGUEIREDO, Henrique Cesar Pereira
RAMOS, Juliana Nunes
VIEIRA, Verônica Viana
FARFOUR, Eric
GUISO, Nicole
HIRATA JÚNIOR, Raphael
AZEVEDO, Vasco Ariston de Carvalho
SILVA, Artur Luiz da Costa da
RAMOS, Rommel Thiago Juca
Institución
Resumen
Non-diphtheriae Corynebacterium species have been increasingly recognized as the causative agents
of infections in humans. Differential identification of these bacteria in the clinical microbiology
laboratory by the most commonly used biochemical tests is challenging, and normally requires
additional molecular methods. Herein, we present the annotated draft genome sequences of two
isolates of “difficult-to-identify” human-pathogenic corynebacterial species: C. xerosis and C.
minutissimum. The genome sequences of ca. 2.7 Mbp, with a mean number of 2,580 protein en coding genes, were also compared with the publicly available genome sequences of strains of C.
amycolatum and C. striatum. These results will aid the exploration of novel biochemical reactions to
improve existing identification tests as well as the development of more accurate molecular
identification methods through detection of species-specific target genes for isolate’s identification
or drug susceptibility profiling. CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior FAPESB - Fundação de Amparo à Pesquisa do Estado da Bahia VERAS, A. A. O.; GUIMARÃES, L. C.; SILVA, A. L. C.; RAMOS, R. T. J. Universidade Federal do Pará