This work aimed to study the effects of coating a thin film of Silicon Carbide and chromium interlayer on the fatigue behavior of Ti-6Al-4V alloy and the correspondent failure evaluation. In the characterization of the layer, the roughness, thickness, and adhesion were determined. Uniaxial fatigue tests were performed under R = 0.1 and the fracture surfaces and corresponding failure mechanisms were observed and identified by SEM, respectively. In the specimens coated using the DC source the number of cycles to failure of the fatigue was increased. The fracture surfaces showed that the crack initiation occurred in the internal regions of the specimens and not superficially. In this case, the layer remained adhered to the specimens even after the tests, showing the effectiveness of the film. In specimens coated using the HiPIMS source, the number of cycles to failure decreased, the cracks were mostly superficial, and the deposited film showed low adhesion after the tests. It proved to be ineffective, worsening the material fatigue behavior.Coordena????o de Aperfei??oamento de Pessoal de N??vel Superior (CAPES)Funda????o para a Ci??ncia e a Tecnologia (FCT)CAPES: 001; 88887.583658/2020-00FCT: 50022/2020