The objective of this study was to evaluate the effects of injectable trace minerals (ITM) on growth, health, antioxidant enzyme activity, and immune system of newborn Boer kids. Newborn kids (n = 125) were assigned to one of two treatments: injection (0.1 mL 4.5 kg−1) of saline or ITM. Injectable trace minerals had 60, 10, 5, and 15 mg mL−1 of Zn, Mn, Se, and Cu, respectively. Kids were evaluated daily for the presence of diarrhea and weighted on d 0, 28, and 56. Blood samples were obtained on d 0, 3, 7, 14, 28, and 56. The ITM injection increased the plasma concentration of superoxide dismutase (d 14), glutathione peroxidase (d 3 and 7), and blood platelets (d 7) compared with saline injection. Kids receiving ITM showed greater amount of blood eosinophils and less mean corpuscular hemoglobin (MCH; d 3) and mean corpuscular hemoglobin concentration (MCHC) compared with kids receiving saline injection. The ITM injection did not affect other components of leukogram and erytogram. The ITM-injected kids tended to have less diarrhea incidence compared with saline-injected kids (20.7 vs. 34.8±7.10% respectively). The ITM injection did not affect mortality rate and growth. Therefore, a single ITM injection administered to newborn Boer kids increases the plasma concentration of antioxidant enzymes, platelets, and eosinophils, reduces MCH, MCHC, and tends to reduce the incidence of diarrhea, but does not affect mortality and growth