Article
Clinical and histopathologic features of canine tegumentary leishmaniasis and the molecular characterization of Leishmania braziliensis in dogs
Registro en:
LAGO, Jamile et al. Clinical and histopathologic features of canine tegumentary leishmaniasis and the molecular characterization of Leishmania braziliensis in dogs. Plos Neglected Tropical Diseases, v. 13, n. 7, p. 1-14, 2019.
1935-2727
10.1371/journal.pntd.0007532
Autor
Lago, Jamile
Silva, Juliana Almeida
Borja, Lairton Souza
Fraga, Deborah Bittencourt Mothé
Schriefer, Albert
Arruda, Sergio
Lago, Ednaldo
Carvalho, Edgar Marcelino de
Bacellar, Maria Olívia Amado Ramos
Resumen
National Institute of Health (NIH) grant AI136032. EMC is a PI of the grant. JL was a fellow from CAPES, Finance Code 001. Cutaneous leishmaniasis (CL), caused by Leishmania braziliensis, is the most important presentation of tegumentary leishmaniasis (TL) in Latin American. While the role of dogs as reservoirs of Leishmania infantum, and the clinic features of canine visceral leishmanisis are well described, little is known about the importance of dogs in the transmission of L. braziliensis to humans. In the present study, we determine the frequency of L. braziliensis infection in dogs with cutaneous and mucosal ulcers in an endemic area of CL. We also describe the clinical manifestations and histopathologic features, and determine if the parasites isolated from dogs are genetically similar to those found in humans.