Article
Use of the Kala-Azar detect and IT-LEISH rapid tests for the diagnosis of visceral leishmaniasis in Brazil
Registro en:
MAGALHAES, Vanessa Peruhype; ASSIS, Tália Santana Machado de; RABELLO, Ana Lucia Teles. Use of the Kala-Azar detect and IT-LEISH rapid tests for the diagnosis of visceral leishmaniasis in Brazil. Memórias do Instituto Oswaldo Cruz. (Online), 2012, vol.107, pp. 951-952
0074-0276
10.1590/S0074-02762012000700019
Autor
Magalhães, Vanessa Peruhype
Assis, Tália Santana Machado de
Rabello, Ana Lúcia Teles
Resumen
The performances of two rapid tests and a standard serological test for the diagnosis of visceral leishmaniasis (VL) were compared using sera from 193 patients with VL and 85 controls. The Kala-Azar Detect®, IT-LEISH® and IFI-LH® assays showed sensitivities of 88.1%, 93.3% and 88.6%, respectively, and specificities of 90.6%, 96.5% and 80%, respectively. The sensitivity values were similar for both rapid tests, but the specificity and positive predictive values of IT-LEISH® were higher than the corresponding values for IFI-LH®. Both rapid tests showed satisfactory performances and can be used in primary health care settings; however, IT-LEISH® permits the use of whole blood, making this assay more suitable for bedside diagnosis.