Article
Frequency of serovars and antimicrobial resistance in Shigella spp. from Brazil
Registro en:
PEIRANO, Gisele; SOUZA, Flávia dos Santos; RODRIGUES, Dalia dos Prazeres. Frequency of serovars and antimicrobial resistance in Shigella spp. from Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 101, n. 3, p. 245-250, May 2006.
0074-0276
10.1590/S0074-02762006000300003
1678-8060
Autor
Peirano, Gisele
Souza, Flávia dos Santos
Rodrigues, Dália dos Prazeres
Resumen
A total of 296 Shigella spp. were received from State Public Health Laboratories, during the period from 1999 to 2004, by National Reference Laboratory for Cholera and Enteric Diseases (NRLCED) - IOC/Fiocruz, Rio de Janeiro, Brazil. The frequency of Shigella spp. was: S. flexneri (52.7%), S. sonnei (44.2%), S. boydii (2.3%), and S. dysenteriae (0.6%). The most frequent S. flexneri serovars were 2a and 1b. The highest incidence rates of Shigella isolation were observed in the Southeast (39%) and Northeast (34%) regions and the lowest rate in the South (3%) of Brazil. Strains were further analyzed for antimicrobial susceptibility by disk diffusion method as part of a surveillance program on antimicrobial resistance. The highest rates of antimicrobial resistance were to trimethoprimsulfamethozaxole (90%), tetracycline (88%), ampicillin (56%), and chloramphenicol (35%). The patterns of antimicrobial resistance among Shigella isolates pose a major difficulty in the determination of an appropriate drug for shigellosis treatment. Continuous monitoring of antimicrobial susceptibilities of Shigella spp. through a surveillance system is thus essential for effective therapy and control measures against shigellosis.