Article
Malaria and Hantavirus Pulmonary Syndrome in Gold Mining in the Amazon Region, Brazil
Registro en:
TRETEL, Ana Cláudia Pereira Terças et al. Malaria and Hantavirus Pulmonary Syndrome in Gold Mining in the Amazon Region, Brazil. International Journal of Environmental Research and Public Health, v. 16, n. 1852, p. 1-11, 2019.
1661-7827
10.3390/ijerph16101852
1660-4601
Autor
Trettel, Ana Cláudia Pereira Terças
Oliveira, Elaine Cristina de
Fontes, Cor Jesus Fernandes
Melo, Alba Valéria Gomes de
Oliveira, Renata Carvalho de
Guterres, Alexandro
Fernandes, Jorlan
Silva, Raphael Gomes da
Atanaka, Marina
Espinosa, Mariano Martinez
Lemos, Elba Regina S.
Resumen
People living in mining regions are exposed to numerous biological agents by several specific types of transmission mechanisms. This study is designed to describe fatal hantavirus pulmonary syndrome (HPS) cases confirmed by serology and molecular analysis, where a seroprevalence survey was conducted in the gold mining regions of the state of Mato Grosso, in the o cial Amazon region, Brazil. Two fatal cases of HPS were confirmed in a mining area in the Legal Amazon, where malaria is one of the most important public health problems. A molecular analysis detected the presence of the genome of the Castelo dos Sonhos virus. Out of the 112 blood samples analyzed, five were positive for Plasmodium infection (four P. falciparum and one P. vivax), and four were seropositive for hantavirus, showing a seroprevalence of 3.57%. One of the four miners who was seroreactive for hantavirus concomitantly had P. falciparum infection, which was confirmed by thick blood smear. This manuscript highlights the importance of considering hantavirus pulmonary syndrome as a diagnostic possibility in febrile infection associated with pulmonary manifestations in mining areas where malaria cases are often identified.