Article
Evaluation of MCM-2 expression in TMA cervical specimens
Registro en:
NICOL, Alcina F. et al. Evaluation of MCM-2 Expression in TMA Cervical Specimens. Plos One, v. 7, n. 4, p. 1-7, Apr. 2012.
1932-6203
10.1371/journal.pone.0032936
Autor
Nicol, Alcina F.
Silva, José R. Lapa e
Cunha, Cynthia B.
Amaro Filho, Sérgio Menezes
Oliveira, Nathalia
Grinsztejn, Beatriz
Friedman, Ruth Khalili
Russomano, Fabio
Pires, Andrea
Golub, Jonathan E.
Nuovo, Gerard J.
Resumen
Minichromosome maintenance proteins (MCM) are highly expressed in actively replicating cells. The need for biological markers for cervical carcinoma and its precursor lesions is emerging. Our main aim was to determine the immunohistochemical expression of MCM-2 in HIV-positive and -negative dysplastic cervical specimens.