Variants in the Toll-Like Receptor Signaling Pathway and Clinical Outcomes of Malaria

Leoratti, Fabiana M. S.; Farias, Lilian; Alves, Fabiana P.; Suarez-Mutis, Martha C.; Coura, José Rodrigues; Kalil, Jorge; Camargo, Erney P.; Moraes, Sandra L.; Ramasawmy, Rajendranath

Article

Registration in:

LEORATTI, Fabiana M. S. et al. Variants in the Toll-Like Receptor Signaling Pathway and Clinical Outcomes of Malaria. The Journal of Infectious Diseases, v. 198, p. 772-780, 2008.

0022-1899

https://www.arca.fiocruz.br/handle/icict/32753

10.1086/590440

1537-6613

https://repositorioslatinoamericanos.uchile.cl/handle/2250/8877050

Author

Leoratti, Fabiana M. S.

Farias, Lilian

Alves, Fabiana P.

Suarez-Mutis, Martha C.

Coura, José Rodrigues

Kalil, Jorge

Camargo, Erney P.

Moraes, Sandra L.

Ramasawmy, Rajendranath

Institutions

Instituto de Comunicação e Informação Científica e Tecnológica em Saúde (Brasil)

Abstract

Malaria is one of the most significant infectious diseases in the world and is responsible for a large proportion of infant deaths. Toll-like receptors (TLRs), key components of innate immunity, are central to countering infection. Variants in the TLR-signaling pathway are associated with susceptibility to infectious diseases.

2022-01-01

Subjects

Malária

Resultados clínicos

Receptor do tipo Toll

Malaria

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