Susceptibility of Nectomys rattus (Pelzen, 1883) to experimental infection with Schistosoma mansoni (Sambon, 1907): a potential reservoir in Brazil

dc.creatorRibeiro, Ana Cláudia
dc.creatorMaldonado Júnior, Arnaldo
dc.creatorD'Andrea, Paulo Sérgio
dc.creatorVieira, Giovane Oliveira
dc.creatorRey, Luís
dc.date2019-09-26T16:01:00Z
dc.date2019-09-26T16:01:00Z
dc.date1998
dc.date.accessioned2023-09-26T22:15:12Z
dc.date.available2023-09-26T22:15:12Z
dc.identifierRIBEIRO Ana Cláudia et al. Susceptibility of Nectomys rattus (Pelzen, 1883) to Experimental Infection with Schistosoma mansoni (Sambon, 1907): a Potential Reservoir in Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 93, Suppl. I, p. 295-299, 1998.
dc.identifier0074-0276
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/35933
dc.identifier10.1590/s0074-02761998000700058
dc.identifier1678-8060
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8876870
dc.descriptionThe aim of the present research was to evaluate the potential of Nectomys rattus, the "water rat", to develop Schistosoma mansoni infection. Comparison with N. squamipes was carried out. Both species of rodents were submitted to transcutaneous infection using different infective cercariae loads: 50, 100 or 500. N. rattus showed high susceptibility to S. mansoni, with an infection rate of 71%. Rodents were able to excrete viable eggs of S. mansoni in the faeces during all infection period. For both species, the small intestine, followed by the liver and the large intestine, presented the highest concentration of eggs among the surveyed organs. Infection caused no animal death. Moreover, N. rattus accomplished the parasite's life cycle, by infecting the snails Biomphalaria glabrata and later Mus musculus. These evidences indicate that both N. rattus, as for N. squamipes are potential reservoirs for schistosomiasis in Brazil. Considering the fact that N. rattus and N. squamipes exist in the same natural ecosystems of S. mansoni, we suggest that these rodents must be regarded as influential factors in epidemiology surveys.
dc.formatapplication/pdf
dc.languageeng
dc.publisherFundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.rightsopen access
dc.subjectSchistosoma mansoni
dc.subjectNectomys rattus
dc.subjectNectomys squamipes
dc.subjectInfecção experimental
dc.subjectRoedores selvagens
dc.subjectNectomys squamipes
dc.subjectNectomys rattu
dc.subjectWild rodent
dc.subjectSchistosoma mansoni
dc.subjectExperimental infection
dc.titleSusceptibility of Nectomys rattus (Pelzen, 1883) to experimental infection with Schistosoma mansoni (Sambon, 1907): a potential reservoir in Brazil
dc.typeArticle


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