Article
Schistosome genomes: a wealth of information.
Registro en:
WEBSTER, Joanne P. et al. Schistosome genomes: a wealth of information. Trends Parasitol. 2010 Mar;26(3):103-6.
1471-4922
10.1016/j.pt.2009.12.006
Autor
Webster, Joanne P.
Oliveira, Guilherme Corrêa de
Rollinson, David
Gower, Charlotte M.
Resumen
The blood flukes Schistosoma japonicum and Schistosoma mansoni are the first major human platyhelminth pathogens to have their genome sequences published. The work of two large international consortia offers draft sequence information and detailed analyses presenting a wealth of information addressing, in particular, metabolic and signalling pathways, host-parasite interactions and potential new drug targets. We comment on these breakthroughs and their potential applications in the study and control of schistosomes.