Article
COVID-19 Infection and Neuropathological Features
Registro en:
LIMA, Leonardo Freire de et al. COVID-19 Infection and Neuropathological Features. Medicines, v. 8, n. 59, p. 1-4, Oct. 2021.
0025-7974
10.3390/medicines8100059
1536-5964
Autor
Lima, Leonardo Freire de
Scovino, Aline Miranda
Fonseca, Leonardo Marques da
Menezes, Camilla Cristie Barreto
Santos, Carlos Antonio do Nascimento
Lima, Marco Edilson Freire de
Decote-Ricardo, Debora
Lima, Matheus Freire de
Costa, Kelli Monteiro da
Reis, Jhenifer Santos dos
Santos, Marcos André Rodrigues da Costa
Lima, Celio Geraldo Freire de
Morrot, Alexandre
Resumen
The pathology associated with COVID-19 infection is progressively being revealed. Recent postmortem assessments have revealed acute airway inflammation as well as diffuse alveolar damage, which bears resemblance to severe acute respiratory syndromes induced by both SARS-CoV and MERS-CoV infections. Although recent papers have highlighted some neuropathologies associated with COVID-19 infection, little is known about this topic of great importance in the area of public health. Here, we discuss how neuroinflammation related to COVID-19 could be triggered by direct viral neuroinvasion and/or cytokine release over the course of the infection.