Article
Increased functional and structural skin capillary density in type 1 diabetes patients with vascular complications
Registro en:
TIBIRIÇÁ, Eduardo; et al. Increased functional and structural skin capillary density in type 1 diabetes patients with vascular complications. Diabetology & Metabolic System, v.1:24, 4p, Dec. 2009.
1758-5996
10.1186/1758-5996-1-24
Autor
Tibiriçá, Eduardo
Rodrigues, Elba
Cobas, Roberta
Gomes, Marilia B.
Resumen
The present study was designed to study skin capillary density and recruitment of the upper and lower extremities in patients with type 1 diabetes with vascular complications, when compared to patients without complications and healthy subjects. We used intravital video-microscopy to measure basal and maximal (during venous congestion) skin capillary densities as well as capillary recruitment using post-occlusive reactive hyperemia (PORH) in the dorsum of the fingers and toes.Our results showed that besides microvascular vasodilation and loss of autoregulatory capacity, patients with type 1 diabetes with vascular complications present increased skin capillary density in both extremities.