Inactivation and Removal of Chikungunya Virus and Mayaro Virus from Plasma-derived Medicinal Products

dc.creatorYue, Constanze
dc.creatorTeitz, Sebastian
dc.creatorMiyabashi, Tomoyuki
dc.creatorBoller, Klaus
dc.creatorLewis-Ximenez, Lia Laura
dc.creatorBaylis, Sally A.
dc.creatorBlümel, Johannes
dc.date2019-07-16T14:15:35Z
dc.date2019-07-16T14:15:35Z
dc.date2019
dc.date.accessioned2023-09-26T20:55:34Z
dc.date.available2023-09-26T20:55:34Z
dc.identifierYUE, Constanze et al. Inactivation and Removal of Chikungunya Virus and Mayaro Virus from Plasma-derived Medicinal Products. Viruses, v. 11, n. 234, p. 1-13, 2019.
dc.identifier1999-4915
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/34147
dc.identifier10.3390/v11030234
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8866274
dc.descriptionChikungunya virus (CHIKV) and Mayaro virus (MAYV) are closely related members of the Semliki Forest complex within the genus alphavirus and are transmitted by arthropods, causing acute febrile illness in humans. CHIKV has spread to almost all continents, whereas autochthonous MAYV infections have been reported in South America and in the Caribbean. Nevertheless, there was concern about potential spread of MAYV to other regions similar to CHIKV in the past. The risk for transmission of emerging viruses by blood transfusion and the safety of plasma-derived medicinal products (PDMPs) are constant concerns. The manufacturing processes of PDMPs include procedures to inactivate/remove viruses.
dc.formatapplication/pdf
dc.languageeng
dc.publisherMDPI
dc.rightsopen access
dc.subjectAlphavirus
dc.subjectNanofiltração
dc.subjectInativação
dc.subjectVírus Chikungunya
dc.subjectTratamento S / D
dc.subjectTratamento térmico
dc.subjectFiltragem retentiva de vírus
dc.subjectMayaro vírus
dc.subjectMedicamentos derivados de plasma
dc.subjectAlphaviruses
dc.subjectInactivation
dc.subjectHeat treatment
dc.subjectS/D treatment
dc.subjectChikungunya virus
dc.subjectMayaro virus
dc.subjectVirus retentive filtration
dc.subjectNanofiltration
dc.subjectPlasma-derived medicinal products
dc.subjectNanofiltração
dc.titleInactivation and Removal of Chikungunya Virus and Mayaro Virus from Plasma-derived Medicinal Products
dc.typeArticle


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