Papers presented at events
Evaluation of anti-Trypanosoma cruzi activities of nitrosyl/nitro ruthenium complexes in vitro and in vivo
Registro en:
BASTOS, T. M. et al. Evaluation of anti-Trypanosoma cruzi activities of nitrosyl/nitro ruthenium complexes in vitro and in vivo. In: CONGRESSO INTERNACIONAL DE MEDICINA TROPICAL E MALÁRIA, 18 e CONGRESSO DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 48., 2012, Rio de Janeiro. Resumos... Rio de Janeiro: Sociedade Brasileira de Medicina Tropical, 2012.
Autor
Bastos, Tanira Matutino
Barbosa, Marília Imaculada Frazão
Meira, Cássio Santana
Guimarães, Elisalva Teixeira
Batista, Alzir Azevedo
Soares, Milena Botelho Pereira
Resumen
CNPq, CAPES, PRONEX and FAPESP enznidazole has been used to treat Chagas disease since the decade of 70ies. Both drugs are effective in
acute phase or recent chronic phase of the disease, but they can induce side effects for the patients.
Therefore, more efficient drugs with lower toxicity are need for the treatment of this disease. Synthesis
of transition metal compounds, especially ruthenium, has increased over the years and data have shown
many biological applications of these compounds.