Article
Epidemiological Survey of Human Alphaherpesvirus 2 (HSV-2) Infection in Indigenous People of Dourados Municipality, Central Brazil
Registro en:
BONFIM, Flávia Freitas de Oliveira et al. Epidemiological Survey of Human Alphaherpesvirus 2 (HSV-2) Infection in Indigenous People of Dourados Municipality, Central Brazil. Tropical Medicine and Infectious Disease, v. 8, p. 1-15, Mar. 2023.
2414-6366
10.3390/tropicalmed8040197
Autor
Bonfim, Flávia Freitas de Oliveira
Villar, Livia Melo
Croda, Julio
Silva, Solange Rodrigues da
Gonçalves, Crhistinne Cavalheiro Maymone
Castro, Vivianne de Oliveira Landgraf de
Romeira, Grazielli Rocha de Rezende
Cesar, Gabriela Alves
Weis-Torres, Sabrina Moreira dos Santos
Horta, Marco Aurélio
Simionatto, Simone
Castro, Ana Rita Coimbra Motta
Paula, Vanessa Salete de
Resumen
Abstract: Sexually transmitted Human alphaherpesvirus 2 (HSV-2) causes genital ulcers, especially
among sexually active adolescents and adults. We estimated the exact prevalence of anti-HSV-
2 antibodies and correlated it with the demographic and behavioral aspects of the Indigenous
population of the Jaguapirú and Bororó villages (Dourados, Mato Grosso do Sul (MS), Brazil). In total,
1360 individuals (>18 years old) were administered serologic tests. The prevalence of anti-HSV-2 IgM
was 12.9%, that of anti-HSV-2 IgG was 57.2%, and 8.5% cases tested positive for both HSV-2 IgM
and IgG. The prevalence of anti-HSV-2 antibodies was higher in females (59.5%) compared to males
(49%), with an OR of 0.64 (0.49–0.83). Anti-HSV-2 antibodies were found in 14.2%, 12.3%, 15.4%, and
14.5% of participants with urinary problems, genital wounds, genital warts, and urethral discharge,
respectively. In summary, the seroprevalence of HSV-2 in the Indigenous population was five times
higher than that reported in the general adult Brazilian population. Educational level, income level,
smoking, condom use, incarceration, illicit drug abuse, the sharing of used needles and syringes
without adequate disinfection, homosexual relationships, prostitution, the sexual practices among
drug users, and avoidance of contraceptive methods could contribute to the facilitation of HSV-2
transmission in the Indigenous population. Our results may help develop culturally appropriate
intervention programs that eliminate health-access barriers and improve the implementation of public
health policies aimed at promoting information regarding and preventing, treating, and controlling
HSV-2 infection in Brazilian Indigenous populations.