Article
Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results
Registro en:
MENDONÇA, Vanessa Amaral et al. Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results. Rev Soc Bras Med Trop., v. 41, Suppl 2, p. 95-98, 2008. doi: 10.1590/s0037-86822008000700019.
0037-8682
10.1590/S0037-86822008000700019
Autor
Mendonca, Vanessa Amaral
Teixeira, Antônio Lúcio
Melo, Gustavo Eustáquio Brito Alvim de
Teixeira, Mauro Martins
Martins Filho, Olindo Assis
Antunes, Carlos Maurício
Teixeira, Antônio Lúcio
Resumen
Neste estudo, a expressão de receptores de quimiocinas na superfície dos leucócitos circulantes foi feita pela citometria de fluxo. Houve aumento da porcentagem de linfócitos CCR2+CD4+ no sangue periférico dos pacientes com hanseníase. Este resultado preliminar sugeriu alteração do perfil dos receptores de quimiocinas desses pacientes. In this study, the expression of chemokine receptors on the surface of circulating leukocytes was determined using flow cytometry. An increase in the percentage of CCR2+CD4+ lymphocytes was observed in the peripheral blood of leprosy patients. This preliminary data suggests that alterations occur in die chemokine receptor profile of these patients