Article
Malignant adenomyo-epithelioma in a feline mammary gland
Registro en:
CAMPOS, C. B. et al. Malignant adenomyo-epithelioma in a feline mammary gland. Only Journal of Veterinary Research, v. 19, n. 3, p. 155-161, 2015.
1328-925X
Autor
Campos, Cecília Bonolo de
Gamba, Conrado de Oliveira
Damasceno, Karine Araújo
Lavalle, Gleidice Eunice
Cassali, Giovanni Dantas
Resumen
Damasceno, Karine Araújo “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”. Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP), Fundação de Amparo a Pesquisa de Minas Gerais (FAPEMIG), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) and
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES). Mammary neoplasms are the third most frequent tumor in felines. We describe
clinical, histopathological, and immuno-histochemical findings from a malignant
adenomyo-epithelioma (MA) from a domestic queen. The cat presented with
mammary masses and underwent radical unilateral mastectomy followed by
chemotherapy. The tumor recurred and the animal survived 125 days but then died.
Microscopy revealed a highly cellular malignant myoepithelial solid cell proliferation
pattern with moderate pleomorphism and malignant epithelial proliferation in a
tubular and papillary arrangement. The myoepithelial nature of the neoplastic cells
was confirmed by p63 target antigen clone test. Based on histopathological and
immunohistochemical findings and histological similarity between women and feline
tumors, a diagnosis of MA was made.