Article
RFC-1 80G>A polymorphism in case-mother/control-mother dyads is associated with risk of nephroblastoma and neuroblastoma
Registro en:
AZEVEDO, Rafaela Montalvão de; et al. RFC-1 80G > A Polymorphism in Case-Mother/ Control-Mother Dyads Is Associated with Risk of Nephroblastoma and Neuroblastoma. Genetic Testing and Molecular Biomarkers, v.19, n.2, p.75-81, 2015.
1945-0265
10.1089/gtmb.2014.0177
1945-0257
Autor
Azevedo, Rafaela Montalvão de
Vasconcelos, Gisele M.
Vargas, Fernando R.
Thuler, Luiz Claudio
Oliveira, Maria S. Pombo de
Camargo, Beatriz de
Resumen
Acknowledgments for a listing of the Brazilian Embryonic Tumor Group. Embryonic tumors are associated with an interruption during normal organ development; they may be related to disturbances in the folate pathway involved in DNA synthesis, methylation, and repair. Prenatal supplementation with folic acid is associated with a decreased risk of neuroblastoma, brain tumors, retinoblastoma, and nephroblastoma. The aim of this study was to investigate the association between MTHFR rs1801133 (C677T) and RFC-1 rs1051266 (G80A) genotypes with the risk of developing nephroblastoma and neuroblastoma. 2030-01-01