Article
Histopathological findings of an uncommon co-infection: Echinococcus vogeli, HIV, hepatitis C virus, and hepatitis B virus
Registro en:
ALMEIDA, Fernanda Barbosa de; et al. Histopathological findings of an uncommon co-infection: Echinococcus vogeli, HIV, hepatitis C virus, and hepatitis B virus. International Journal of Infectious Diseases, v.17, n.10, e925–e927, 2013.
1201-9712
10.1016/j.ijid.2013.04.002
Autor
Almeida, Fernanda Barbosa de
Corrêa, Christiane Leal
Siqueira, Nilton Ghiotti de
Carvalho, Nellysie Virgínia F. M. dos S. Castro de
Silva, Rosângela Rodrigues
Andrade, Arnaldo Feitosa B. de
Silva, Arnaldo Feitosa B. de
Resumen
Our work represents the first case report of polycystic echinococcosis co-infection with HIV, hepatitis C
virus (HCV), and hepatitis B virus (HBV). Structural liver alterations were found to be related to parasitic
structures and necroinflammatory foci (karyopyknosis, karyorrhexis, and karyolysis), consistent with
Echinococcus vogeli. Visceral adipose tissue and intrahepatic triglyceride droplets (macrovesicular and
microvesicular steatosis) indicated abnormal fat anabolism, which probably resulted from both viral-
induced hepatopathy and drug-related toxicity. In summary, our results suggest that the observed liver
abnormalities reflected the coincident exposure to hepatotropic viruses and parasites causing polycystic
echinococcosis and were not indicative of opportunistic relationships among these pathogens.