Article
Implications of high level pseudogene transcription in Mycobacterium leprae
Registro en:
WILLIAMS, Diana L. et al. Implications of high level pseudogene transcription in Mycobacterium leprae. BMC Genomics, v.10, n.397, 20p, Aug. 2009.
1471-2164
10.1186/1471-2164-10-397
Autor
Williams, Diana L.
Slayden, Richard A.
Amin, Amol
Martinez, Alejandra N.
Pittman, Tana L.
Mira, Alex
Mitra, Anirban
Nagaraja, Valakunja
Morrison, Norman E.
Moraes, Milton
Gillis, Thomas P.
Resumen
The Mycobacterium leprae genome has less than 50% coding capacity and 1,133 pseudogenes. Preliminary evidence suggests that some pseudogenes are expressed. Therefore, defining pseudogene transcriptional and translational potentials of this genome should increase our understanding of their impact on M. leprae physiology.