Preprint
Global Disparities in Skin Cancer Services at HIV Treatment Centers across 29 Countries
Registro en:
MCMAHON, Devon E. et al. Global Disparities in Skin Cancer Services at HIV Treatment Centers across 29 Countries. The Journal of investigative dermatology, v. 141, n. 10, p. 2533-2536, 2021.
0022-202X
10.1016/j.jid.2021.02.758
Autor
McMahon, Devon E.
Semeere, Aggrey
Laker-Oketta, Miriam
Byakwaga, Helen
Mugglin, Catrina
Duda, Stephany N.
Azwa, Iskandar
Jaquet, Antoine
Cardoso, Sandra W.
Nash, Denis
Wester, C. William
Freeman, Esther E.
International Epidemiology Databases to Evaluate AIDS (IeDEA)
Resumen
More than two thirds of global cancer deaths occur in LMICs due in part to delayed diagnosis and lack of
access to specialized staff, chemotherapy and radiation.(Livingston, 2013) Cutaneous malignancies are common
and morbid in LMICs, particularly for people living with HIV.(Bray et al., 2018, McMahon et al., 2020) People living
with HIV develop more AIDS-defining and non-AIDS defining skin cancers compared to the general population,
including Kaposi sarcoma (KS), human papillomavirus (HPV)-associated squamous cell carcinomas, cutaneous
lymphoma, keratinocyte carcinomas and melanoma.(Chelidze et al., 2019, Jaquet et al., 2015, WHO, 2014) KS in
particular continues to be the leading cause of cancer incidence and mortality across the general population of
Malawi, Mozambique, Uganda, and Zambia.(Bray et al., 2018) Although the majority of people living with HIV
reside in LMICs – including 25.6 million people in sub-Saharan Africa – little is known about LMIC capacity to
diagnose and manage skin cancers.