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Immunopathological response in mice with triple infection with Trypanosoma cruzi strains of different Biodemes submitted to treatment with immunossupressor drugs
Registro en:
MAGALHÃES, L. A. et al. Immunopathological response in mice with triple infection with Trypanosoma cruzi strains of different Biodemes submitted to treatment with immunossupressor drugs. In: CONGRESSO INTERNACIONAL DE MEDICINA TROPICAL E MALÁRIA, 18 e CONGRESSO DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 48., 2012, Rio de Janeiro. Resumos... Rio de Janeiro: Sociedade Brasileira de Medicina Tropical, 2012.
Autor
Magalhães, Lorena dos Anjos
Souza Junior, A. F
Guerreiro, Marcos Lázaro da Silva
Andrade, Sonia Gumes
Resumen
Introduction: An important factor that contributes to the severity of Chagas disease in people
living in endemic areas is the occurrence of multiple infections with Trypanosoma cruzi.
Experimental studies have shown the increased morbidity due to successive reinfections with
different strains, with the possibility of to evaluate the influence of multiple infections upon the
tissue lesions. Multiple infections could also influence an activation of the disease in patients
with HIV infection (AIDs) or immunosuppressed in cases of organs transplantation. In such
cases, a reactivation of virulent strains could occur with aggravation of the disease. Objective:
to evaluate the immunopathological response in mice triple infected with different T. cruzi
strains and treated with immunosuppressor drugs.